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Tbio
HCLS1
Hematopoietic lineage cell-specific protein

Protein Summary
Description
Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000314583
  • ENSP00000320176
  • ENSG00000180353
  • ENST00000495491
  • ENSP00000418299

Symbol
  • HS1
  • HS1
  • p75
  • CTTNL
  • lckBP1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
0.87
gene perturbation
0.81
kinase
0.78
virus perturbation
0.76
hub protein
0.71


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.92   (req: < 5)
Gene RIFs: 16   (req: <= 3)
Antibodies: 428   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.92   (req: >= 5)
Gene RIFs: 16   (req: > 3)
Antibodies: 428   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 26
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0