HAS2
Hyaluronan synthase 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.98 | ||
PubMedID | 0.97 | ||
pathway | 0.92 | ||
biological process | 0.85 | ||
transcription factor perturbation | 0.8 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Glycosaminoglycan metabolism | ||||
Reactome | Hyaluronan biosynthesis and export | ||||
Reactome | Hyaluronan metabolism | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of carbohydrates | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Glycosaminoglycan metabolism | ||||
Hyaluronan biosynthesis and export | ||||
Hyaluronan metabolism | ||||
Metabolism | ||||
Metabolism of carbohydrates | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Mutant Phenotype (IMP) | BHF-UCL | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
hematocrit | 1 | 1 | 1 | 44.2 | |||||
pulse pressure measurement | 1 | 1 | 0 | 4.5 | 33.1 | ||||
self reported educational attainment | 1 | 1 | 0 | 4.5 | 33.1 | ||||
balding measurement | 1 | 1 | 1 | 24.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
hematocrit | 1 | 44.2 | |||||
pulse pressure measurement | 0 | 4.5 | 33.1 | ||||
self reported educational attainment | 0 | 4.5 | 33.1 | ||||
balding measurement | 1 | 24.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:107821 | 15117 | ||||||
Rat | RGD:2781 | 25694 | ||||||
Dog | hyaluronan synthase 2 | VGNC:41600 | 482032 | |||||
Horse | hyaluronan synthase 2 | VGNC:18696 | 100009708 | |||||
Cow | hyaluronan synthase 2 | VGNC:29755 | 281220 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Dog | hyaluronan synthase 2 | |||||
Horse | hyaluronan synthase 2 | |||||
Cow | hyaluronan synthase 2 | |||||
PMID | Year | Title |
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