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Tdark
TMEM178B
Transmembrane protein 178B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000565468
  • ENSP00000456594
  • ENSG00000261115
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.63
tissue sample
0.61
tissue
0.56
PubMedID
0.38
cell line
0.37


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.58   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 4   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.58   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 4   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (27)
ZNF605
Tdark
Family:  TF
Novelty:  3.52112333
Score:  0.617
Data Source:  STRINGDB
OR1Q1
Tdark
Family:  oGPCR
Novelty:  2.34969145
Score:  0.595
Data Source:  STRINGDB
TAS2R3
Tchem
Family:  GPCR
Novelty:  0.09368884
Score:  0.545
Data Source:  STRINGDB
SNCAIP
Tbio
Novelty:  0.01355161
Score:  0.536
Data Source:  STRINGDB
TENT4B
Tbio
Family:  Enzyme
Novelty:  0.06266066
Score:  0.519
Data Source:  STRINGDB
YIPF4
Tdark
Novelty:  0.17862058
Score:  0.518
Data Source:  STRINGDB
MEX3B
Tbio
Novelty:  0.14914846
Score:  0.513
Data Source:  STRINGDB
TAS2R4
Tchem
Family:  GPCR
Novelty:  0.02938385
Score:  0.512
Data Source:  STRINGDB
TMEM59L
Tbio
Novelty:  0.22745646
Score:  0.509
Data Source:  STRINGDB
ANKRD17
Tbio
Novelty:  0.03177323
Score:  0.506
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist circumference
1
2
2
31.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist circumference
2
31.3
IDG Resources
No IDG generated resources found
Publication Statistics
PubMed Score 0.58
PubMed score by year
PubTator Score 1.00
PubTator score by year
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Related Publications
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PMID
Year
Title