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Tbio
GTSF1
Gametocyte-specific factor 1

Protein Summary
Description
Required for spermatogenesis and is involved in the suppression of retrotransposon transcription in male germ cells.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000305879
  • ENSP00000304185
  • ENSG00000170627
  • ENST00000552397
  • ENSP00000446485

Symbol
  • FAM112B
  • Cue110
  • FAM112B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.83
tissue sample
0.75
phenotype
0.59
cell type or tissue
0.55
tissue
0.54


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.31   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 90   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.31   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 90   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (49)
RGP1
Tbio
Novelty:  4
p_int:  0.99999641
p_ni:  0.000002422
p_wrong:  0.000001168
Score:  0.485
Data Source:  BioPlex,STRINGDB
MAPK14
Tchem
Family:  Kinase
Novelty:  0.00045138
p_int:  0.999785271
p_ni:  0.000214729
Data Source:  BioPlex
MAEL
Tbio
Novelty:  0.01925239
Score:  0.747
Data Source:  STRINGDB
TEX11
Tbio
Novelty:  0.04868648
Score:  0.711
Data Source:  STRINGDB
TDRD12
Tdark
Family:  Epigenetic
Novelty:  0.2276017
Score:  0.709
Data Source:  STRINGDB
TOPAZ1
Tdark
Novelty:  0.42409276
Score:  0.707
Data Source:  STRINGDB
CCNB2
Tbio
Novelty:  0.00672914
Score:  0.696
Data Source:  STRINGDB
TDRD1
Tbio
Family:  Epigenetic
Novelty:  0.04645566
Score:  0.661
Data Source:  STRINGDB
TDRD9
Tbio
Family:  Epigenetic
Novelty:  0.10913126
Score:  0.634
Data Source:  STRINGDB
ASZ1
Tbio
Novelty:  0.0011137
Score:  0.621
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (4)
Find Similar Targets
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1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
gametocyte specific factor 1
VGNC:5409
451960
Macaque
gametocyte specific factor 1
703716
Mouse
MGI:1921424
74174
Rat
RGD:1310791
315347
Dog
gametocyte specific factor 1
477590
Species
Name
OMA
EggNOG
Inparanoid
Chimp
gametocyte specific factor 1
Macaque
gametocyte specific factor 1
Mouse
Rat
Dog
gametocyte specific factor 1
Publication Statistics
PubMed Score 13.31
PubMed score by year
PubTator Score 3.90
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Text