GPX2
Glutathione peroxidase 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.94 | ||
PubMedID | 0.92 | ||
small molecule perturbation | 0.89 | ||
disease perturbation | 0.83 | ||
transcription factor perturbation | 0.68 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Arachidonic acid metabolism | ||||
Reactome | Cellular responses to external stimuli | ||||
Reactome | Cellular responses to stress | ||||
Reactome | Detoxification of Reactive Oxygen Species | ||||
Reactome | Fatty acid metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Arachidonic acid metabolism | ||||
Cellular responses to external stimuli | ||||
Cellular responses to stress | ||||
Detoxification of Reactive Oxygen Species | ||||
Fatty acid metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean corpuscular volume | 2 | 4 | 4 | 90.5 | |||||
reticulocyte measurement | 3 | 2 | 3 | 90.2 | |||||
mean corpuscular hemoglobin concentration | 2 | 1 | 2 | 88.3 | |||||
reticulocyte count | 2 | 2 | 2 | 86.6 | |||||
mean reticulocyte volume | 1 | 2 | 2 | 84.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean corpuscular volume | 4 | 90.5 | |||||
reticulocyte measurement | 3 | 90.2 | |||||
mean corpuscular hemoglobin concentration | 2 | 88.3 | |||||
reticulocyte count | 2 | 86.6 | |||||
mean reticulocyte volume | 2 | 84.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | glutathione peroxidase 2 | VGNC:12658 | 467483 | |||||
Mouse | MGI:106609 | 14776 | ||||||
Rat | RGD:727780 | 29326 | ||||||
Dog | glutathione peroxidase 2 | VGNC:41462 | 480356 | |||||
Cow | glutathione peroxidase 2 | VGNC:29618 | 533088 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | glutathione peroxidase 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | glutathione peroxidase 2 | |||||
Cow | glutathione peroxidase 2 | |||||
PMID | Year | Title |
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