You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
GPRC5B
G-protein coupled receptor family C group 5 member B

Protein Summary
Description
Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. This gene encodes a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The encoded protein may modulate insulin secretion and increased protein expression is associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000300571
  • ENSP00000300571
  • ENSG00000167191
  • ENST00000535671
  • ENSP00000442858
  • ENST00000569479
  • ENSP00000454727
  • ENST00000569847
  • ENSP00000457283

Symbol
  • RAIG2
  • RAIG2
  • RAIG-2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.85
biological process
0.81
gene perturbation
0.81
histone modification site profile
0.77
molecular function
0.73


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.61   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 289   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.61   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 289   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0