Tbio GPR89A Golgi pH regulator A

Protein Summary

Description

Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance.

Uniprot Accession IDs

• B7ZAQ6
• A6NN37
• B2RUV3
• B3KMN3
• B4DLT3
• B4DXE7
• Q53FQ9
• Q5T2V8
• Q5T5P5
• Q659E2
• Q6NVY5
• Q9P0S4
• Q9Y302

Gene Name

• GPR89A

Ensembl ID

• ENST00000313835
• ENSP00000319673
• ENSG00000117262
• ENST00000460277
• ENSP00000436705
• ENST00000462900
• ENSP00000432248
• ENST00000528944
• ENSP00000434108
• ENST00000534502
• ENSP00000434495

Symbol

• GPHRA
• GPR89
• SH120
• GPHR
• GPR89
• SH120
• GPR89C
• UNQ192

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.78
cellular component	0.66
tissue sample	0.56
tissue	0.55
cell line	0.44

Protein Classes

PANTHER Classes

Protein / Receptor / G-protein Coupled Receptor / Golgi Ph Regulator A

DTO Classes

Protein / Ion Channel / Golgi Ph Regulator Family / Golgi Ph Regulator A

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.05   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 133   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.05   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 133   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0