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Tdark
GPR82
Probable G-protein coupled receptor 82

Protein Summary
Description
Orphan receptor. The protein encoded by this gene is an orphan G protein-coupled receptor of unknown function. The encoded protein is a member of a family of proteins that contain seven transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. [provided by RefSeq, Sep 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000302548
  • ENSP00000303549
  • ENSG00000171657
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.75
cell type or tissue
0.67
cell line
0.52
microRNA
0.48
tissue
0.44


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.17   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 140   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.17   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 140   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (31)
EFHC2
Tbio
Novelty:  0.08795794
Score:  0.834
Data Source:  STRINGDB
GPR142
Tchem
Family:  GPCR
Novelty:  0.08800117
Score:  0.71
Data Source:  STRINGDB
CASK
Tchem
Family:  Kinase
Novelty:  0.00856437
Score:  0.654
Data Source:  STRINGDB
GPR162
Tbio
Family:  GPCR
Novelty:  0.14938549
Score:  0.634
Data Source:  STRINGDB
GPR27
Tbio
Family:  GPCR
Novelty:  0.164488
Score:  0.605
Data Source:  STRINGDB
GPR15
Tbio
Family:  GPCR
Novelty:  0.00673057
Score:  0.575
Data Source:  STRINGDB
GPR52
Tchem
Family:  GPCR
Novelty:  0.07988639
Score:  0.573
Data Source:  STRINGDB
GPR26
Tbio
Family:  GPCR
Novelty:  0.13362837
Score:  0.561
Data Source:  STRINGDB
GPR150
Tdark
Family:  GPCR
Novelty:  0.91287003
Score:  0.559
Data Source:  STRINGDB
GPR61
Tbio
Family:  GPCR
Novelty:  0.11649666
Score:  0.54
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
1
1
1
59.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
1
59.9
IDG Resources
Items per page:
10
1 – 10 of 21
Genetic Construct
GPR82-Tango
image for GPR82-Tango
Details:
  • Vector:  addgene66375
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  FLAG
Data:
  • GPR82-Tango
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Genetic Construct
pcDNA3.1-GGamma13-GFP2
image for pcDNA3.1-GGamma13-GFP2
Details:
  • Vector type:  cDNA
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  not applicable
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Genetic Construct
pcDNA3.1-GGamma9-GFP2
image for pcDNA3.1-GGamma9-GFP2
Details:
  • Vector type:  cDNA
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  not applicable
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Genetic Construct
pcDNA3.1-GGamma8-GFP2
image for pcDNA3.1-GGamma8-GFP2
Details:
  • Vector type:  cDNA
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  not applicable
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Genetic Construct
pcDNA3.1-GGamma1-GFP2
image for pcDNA3.1-GGamma1-GFP2
Details:
  • Vector type:  cDNA
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  not applicable
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Genetic Construct
pcDNA3.1-Beta3
image for pcDNA3.1-Beta3
Details:
  • Vector type:  cDNA
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  not applicable
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Genetic Construct
pcDNA3.1-Beta1
image for pcDNA3.1-Beta1
Details:
  • Vector type:  cDNA
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  not applicable
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Genetic Construct
pcDNA5/FRT/TO-GAlpha13-RLuc8
image for pcDNA5/FRT/TO-GAlpha13-RLuc8
Details:
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Genetic Construct
pcDNA5/FRT/TO-GAlpha12-RLuc8
image for pcDNA5/FRT/TO-GAlpha12-RLuc8
Details:
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Genetic Construct
pcDNA5/FRT/TO-GAlpha15-RLuc8
image for pcDNA5/FRT/TO-GAlpha15-RLuc8
Details:
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Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
G protein-coupled receptor 82
VGNC:2720
100608260
Macaque
G protein-coupled receptor 82
701014
Mouse
MGI:2441734
319200
Rat
RGD:2318147
100362441
Dog
G protein-coupled receptor 82
VGNC:41444
100683784
Species
Name
OMA
EggNOG
Inparanoid
Chimp
G protein-coupled receptor 82
Macaque
G protein-coupled receptor 82
Mouse
Rat
Dog
G protein-coupled receptor 82
Publication Statistics
PubMed Score 3.17
PubMed score by year
PubTator Score 0.46
PubTator score by year
Patents
Patents by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title