Tchem GPR32 Probable G-protein coupled receptor 32

Protein Summary

Description

Orphan receptor. This gene is intronless and encodes a member of the G-protein coupled receptor 1 family. The encoded protein binds to resolvin D1 and lipoxin A4 and has been linked to pulmonary inflammation. A related pseudogene has been identified on chromosome 19. [provided by RefSeq, Nov 2012]

Uniprot Accession IDs

• O75388
• Q502U7
• Q6NWS5

Gene Name

• GPR32

Ensembl ID

• ENST00000270590
• ENSP00000270590
• ENSG00000142511

Symbol

• RVDR1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.69
tissue	0.5
tissue sample	0.43
cell line	0.42
protein domain	0.41

Protein Classes

PANTHER Classes

Protein / Receptor / G-protein Coupled Receptor / Probable G-protein Coupled Receptor 32

DTO Classes

Protein / G-protein Coupled Receptor / Class A Rhodopsin Like / Probable G-protein Coupled Receptor 32

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.35   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 280   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.35   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 280   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 3

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0