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Tbio
GPR160
Probable G-protein coupled receptor 160

Protein Summary
Description
Orphan receptor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000355897
  • ENSP00000348161
  • ENSG00000173890

Symbol
  • GPCR150
  • GPCR1
  • GPCR150
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.72
virus perturbation
0.59
tissue sample
0.52
transcription factor binding site profile
0.5
cell type or tissue
0.45


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.67   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 222   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.67   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 222   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (26)
RPL22
Tbio
Novelty:  0.00473197
Score:  0.901
Data Source:  STRINGDB
ENPEP
Tchem
Family:  Enzyme
Novelty:  0.00112857
Score:  0.758
Data Source:  STRINGDB
KLHL8
Tdark
Novelty:  0.4838314
Score:  0.703
Data Source:  STRINGDB
SLC25A36
Tbio
Family:  Transporter
Novelty:  0.03164907
Score:  0.703
Data Source:  STRINGDB
NXT2
Tdark
Novelty:  0.03767394
Score:  0.649
Data Source:  STRINGDB
CFI
Tbio
Novelty:  0.00271423
Score:  0.642
Data Source:  STRINGDB
BNIPL
Tbio
Novelty:  0.10839456
Score:  0.634
Data Source:  STRINGDB
HNRNPLL
Tbio
Novelty:  0.0498467
Score:  0.627
Data Source:  STRINGDB
GPR107
Tbio
Family:  GPCR
Novelty:  0.11706099
Score:  0.599
Data Source:  STRINGDB
GPRC6A
Tchem
Family:  GPCR
Novelty:  0.01625616
Score:  0.56
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.1
73.3
appendicular lean mass
2
1
2
66.3
diastolic blood pressure
2
1
2
65.7
1
1
0
7.3
61
1
1
0
1.2
50.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.1
73.3
appendicular lean mass
2
66.3
diastolic blood pressure
2
65.7
0
7.3
61
0
1.2
50.9
Find similar targets by:
IDG Resources
Items per page:
10
1 – 10 of 21
Genetic Construct
GPR160-Tango
image for GPR160-Tango
Details:
  • Vector:  addgene66333
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  FLAG
Data:
  • GPR160-Tango
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Genetic Construct
pcDNA3.1-GGamma13-GFP2
image for pcDNA3.1-GGamma13-GFP2
Details:
  • Vector type:  cDNA
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  not applicable
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Genetic Construct
pcDNA3.1-GGamma9-GFP2
image for pcDNA3.1-GGamma9-GFP2
Details:
  • Vector type:  cDNA
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  not applicable
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Genetic Construct
pcDNA3.1-GGamma8-GFP2
image for pcDNA3.1-GGamma8-GFP2
Details:
  • Vector type:  cDNA
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  not applicable
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Genetic Construct
pcDNA3.1-GGamma1-GFP2
image for pcDNA3.1-GGamma1-GFP2
Details:
  • Vector type:  cDNA
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  not applicable
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Genetic Construct
pcDNA3.1-Beta3
image for pcDNA3.1-Beta3
Details:
  • Vector type:  cDNA
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  not applicable
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Genetic Construct
pcDNA3.1-Beta1
image for pcDNA3.1-Beta1
Details:
  • Vector type:  cDNA
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  not applicable
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Genetic Construct
pcDNA5/FRT/TO-GAlpha13-RLuc8
image for pcDNA5/FRT/TO-GAlpha13-RLuc8
Details:
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Genetic Construct
pcDNA5/FRT/TO-GAlpha12-RLuc8
image for pcDNA5/FRT/TO-GAlpha12-RLuc8
Details:
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Genetic Construct
pcDNA5/FRT/TO-GAlpha15-RLuc8
image for pcDNA5/FRT/TO-GAlpha15-RLuc8
Details:
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Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
G protein-coupled receptor 160
VGNC:7973
460993
Macaque
G protein-coupled receptor 160
696917
Mouse
MGI:1919112
71862
Rat
RGD:1560200
499588
Dog
G protein-coupled receptor 160
VGNC:41411
100685878
Species
Name
OMA
EggNOG
Inparanoid
Chimp
G protein-coupled receptor 160
Macaque
G protein-coupled receptor 160
Mouse
Rat
Dog
G protein-coupled receptor 160
Publication Statistics
PubMed Score 9.67
PubMed score by year
PubTator Score 6.22
PubTator score by year
Patents
Patents by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title