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Tbio
GPR152
Probable G-protein coupled receptor 152

Protein Summary
Description
Orphan receptor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000312457
  • ENSP00000310255
  • ENSG00000175514

Symbol
  • PGR5
  • PGR5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.65
tissue sample
0.59
protein domain
0.58
tissue
0.42
phenotype
0.35


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 53.1   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 152   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 53.1   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 152   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (17)
GLIS3
Tbio
Family:  TF
Novelty:  0.0018696
Score:  0.793
Data Source:  STRINGDB
SPX
Tbio
Novelty:  0.00488569
Score:  0.709
Data Source:  STRINGDB
GPR171
Tbio
Family:  GPCR
Novelty:  0.29228187
Score:  0.457
Data Source:  STRINGDB
GPR89A
Tbio
Family:  IC
Novelty:  0.06782776
Score:  0.453
Data Source:  STRINGDB
C11orf24
Tdark
Novelty:  1.70568455
Score:  0.453
Data Source:  STRINGDB
GPR89B
Tbio
Family:  IC
Novelty:  0.06782776
Score:  0.453
Data Source:  STRINGDB
GPR162
Tbio
Family:  GPCR
Novelty:  0.14938549
Score:  0.446
Data Source:  STRINGDB
DECR1
Tbio
Family:  Enzyme
Novelty:  0.02699187
Score:  0.442
Data Source:  STRINGDB
CHP1
Tbio
Novelty:  0.01299969
Score:  0.441
Data Source:  STRINGDB
GPR82
Tdark
Family:  GPCR
Novelty:  0.39696704
Score:  0.437
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean reticulocyte volume
1
3
3
94.9
body height
2
2
2
94.5
mean corpuscular hemoglobin concentration
2
2
2
89
mean corpuscular volume
2
2
2
86.7
IGF-1 measurement
1
2
2
65.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean reticulocyte volume
3
94.9
body height
2
94.5
mean corpuscular hemoglobin concentration
2
89
mean corpuscular volume
2
86.7
IGF-1 measurement
2
65.3
Find similar targets by:
IDG Resources
Genetic Construct
GPR152-Tango
image for GPR152-Tango
Details:
  • Vector:  addgene66328
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  FLAG
Data:
  • GPR152-Tango
Order Genetic Construct from:
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
G protein-coupled receptor 152
721722
Mouse
MGI:2685519
269053
Rat
RGD:1584082
688884
Dog
G protein-coupled receptor 152
VGNC:41406
612997
Horse
G protein-coupled receptor 152
VGNC:18519
100059343
Species
Name
OMA
EggNOG
Inparanoid
Macaque
G protein-coupled receptor 152
Mouse
Rat
Dog
G protein-coupled receptor 152
Horse
G protein-coupled receptor 152
Publication Statistics
PubMed Score 53.10
PubMed score by year
PubTator Score 18.04
PubTator score by year
Patents
Patents by year
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Related Publications
Items per page:
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PMID
Year
Title