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Tdark
GPR137C
Integral membrane protein GPR137C

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000321662
  • ENSP00000315106
  • ENSG00000180998

Symbol
  • TM7SF1L2
  • TM7SF1L2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.82
histone modification site profile
0.81
tissue sample
0.64
cell type or tissue
0.61
transcription factor binding site profile
0.55


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.3   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 68   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.3   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 68   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (41)
TXNDC16
Tdark
Novelty:  0.25365147
Score:  0.799
Data Source:  STRINGDB
GPR157
Tdark
Family:  GPCR
Novelty:  0.96671087
Score:  0.766
Data Source:  STRINGDB
STYX
Tbio
Family:  Enzyme
Novelty:  0.04754929
Score:  0.7
Data Source:  STRINGDB
DDHD1
Tbio
Family:  Enzyme
Novelty:  0.05209502
Score:  0.696
Data Source:  STRINGDB
GPR108
Tbio
Novelty:  0.24228136
Score:  0.661
Data Source:  STRINGDB
GPR107
Tbio
Family:  GPCR
Novelty:  0.11706099
Score:  0.649
Data Source:  STRINGDB
TMEM221
Tdark
Novelty:  6.39119451
Score:  0.646
Data Source:  STRINGDB
TMEM212
Tdark
Novelty:  0.94290731
Score:  0.633
Data Source:  STRINGDB
NID2
Tbio
Novelty:  0.01638372
Score:  0.631
Data Source:  STRINGDB
TMEM211
Tdark
Novelty:  6.51386952
Score:  0.63
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
2
3
3
66.2
urinary metabolite measurement
1
1
1
57.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
66.2
urinary metabolite measurement
1
57.8
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
G protein-coupled receptor 137C
VGNC:7441
743078
Macaque
G protein-coupled receptor 137C
710628
Mouse
MGI:1917963
70713
Rat
RGD:1563070
305812
Dog
G protein-coupled receptor 137C
VGNC:41399
612969
Species
Name
OMA
EggNOG
Inparanoid
Chimp
G protein-coupled receptor 137C
Macaque
G protein-coupled receptor 137C
Mouse
Rat
Dog
G protein-coupled receptor 137C
Publication Statistics
PubMed Score 0.30
PubMed score by year
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Related Publications
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0 of 0
PMID
Year
Title