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Tbio
GPR137B
Integral membrane protein GPR137B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000366592
  • ENSP00000355551
  • ENSG00000077585

Symbol
  • TM7SF1
  • TM7SF1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.94
transcription factor perturbation
0.8
cell type or tissue
0.76
virus perturbation
0.68
histone modification site profile
0.67


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.55   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 121   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.55   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 121   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (36)
DOC2A
Tbio
Novelty:  0.07489914
p_int:  0.999607487
p_ni:  0.000392512
p_wrong:  1e-9
Score:  0.227
Data Source:  BioPlex,STRINGDB
NCAPD2
Tbio
Novelty:  0.04960987
p_int:  0.992627772
p_ni:  0.007371979
p_wrong:  2.49e-7
Score:  0.219
Data Source:  BioPlex,STRINGDB
NCAPH
Tbio
Novelty:  0.01598076
p_int:  0.979404069
p_ni:  0.020595931
Score:  0.356
Data Source:  BioPlex,STRINGDB
NCAPG
Tbio
Novelty:  0.01777557
p_int:  0.969935462
p_ni:  0.030064537
p_wrong:  1e-9
Score:  0.234
Data Source:  BioPlex,STRINGDB
ZYG11B
Tbio
Novelty:  0.14657862
p_int:  0.889364897
p_ni:  0.110635103
Score:  0.187
Data Source:  BioPlex,STRINGDB
SMC2
Tchem
Novelty:  0.06898543
p_int:  0.823212698
p_ni:  0.176787302
Score:  0.219
Data Source:  BioPlex,STRINGDB
GPR107
Tbio
Family:  GPCR
Novelty:  0.11706099
Score:  0.619
Data Source:  STRINGDB
GPR174
Tchem
Family:  GPCR
Novelty:  0.09139622
Score:  0.598
Data Source:  STRINGDB
GPR108
Tbio
Novelty:  0.24228136
Score:  0.594
Data Source:  STRINGDB
TM7SF3
Tbio
Novelty:  0.12188681
Score:  0.568
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
1
1
1
76.2
C-reactive protein measurement
3
2
3
60.1
cortical surface area measurement
1
1
0
5.9
19.6
brain measurement
1
1
0
5.5
12.1
diastolic blood pressure
1
1
1
12.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
1
76.2
C-reactive protein measurement
3
60.1
cortical surface area measurement
0
5.9
19.6
brain measurement
0
5.5
12.1
diastolic blood pressure
1
12.1
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
G protein-coupled receptor 137B
VGNC:8041
457840
Macaque
G protein-coupled receptor 137B
717808
Mouse
MGI:1891463
83924
Dog
G protein-coupled receptor 137B
VGNC:41398
479194
Horse
G protein-coupled receptor 137B
VGNC:18510
100050643
Species
Name
OMA
EggNOG
Inparanoid
Chimp
G protein-coupled receptor 137B
Macaque
G protein-coupled receptor 137B
Mouse
Dog
G protein-coupled receptor 137B
Horse
G protein-coupled receptor 137B
Publication Statistics
PubMed Score 8.55
PubMed score by year
PubTator Score 2.97
PubTator score by year
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Related Publications
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PMID
Year
Title