Tbio GPR107 Protein GPR107

Protein Summary

Description

Involved in Golgi-to-ER retrograde transport. Functions as a host factor required for infection by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT toxins.

Uniprot Accession IDs

• Q5VW38
• A6NJ53
• Q2TB81
• Q5JPA3
• Q5VW39
• Q96T26
• Q9H658
• Q9HCE8

Gene Name

• GPR107

Ensembl ID

• ENST00000347136
• ENSP00000336988
• ENSG00000148358
• ENST00000372406
• ENSP00000361483
• ENST00000610997
• ENSP00000483750

Symbol

• KIAA1624
• LUSTR1
• GCDRP
• LUSTR1
• bA138E2.2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.84
transcription factor binding site profile	0.74
virus perturbation	0.72
histone modification site profile	0.7
tissue sample	0.67

Protein Classes

PANTHER Classes

Protein / Receptor / G-protein Coupled Receptor / Protein Gpr107

DTO Classes

Protein / G-protein Coupled Receptor / Other 7tm Proteins / Lu7tm Family / Protein Gpr107

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.83   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 136   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.83   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 136   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0