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Tbio
GPR107
Protein GPR107

Protein Summary
Description
Involved in Golgi-to-ER retrograde transport. Functions as a host factor required for infection by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT toxins.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000347136
  • ENSP00000336988
  • ENSG00000148358
  • ENST00000372406
  • ENSP00000361483
  • ENST00000610997
  • ENSP00000483750

Symbol
  • KIAA1624
  • LUSTR1
  • GCDRP
  • LUSTR1
  • bA138E2.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.84
transcription factor binding site profile
0.74
virus perturbation
0.72
histone modification site profile
0.7
tissue sample
0.67


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.83   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 136   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.83   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 136   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0