Protein Summary
Involved in Golgi-to-ER retrograde transport. Functions as a host factor required for infection by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT toxins.
- ENST00000347136
- ENSP00000336988
- ENSG00000148358
- ENST00000372406
- ENSP00000361483
- ENST00000610997
- ENSP00000483750
- KIAA1624
- LUSTR1
- GCDRP
- LUSTR1
- bA138E2.2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor perturbation | 0.84 | ||
transcription factor binding site profile | 0.74 | ||
virus perturbation | 0.72 | ||
histone modification site profile | 0.7 | ||
tissue sample | 0.67 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 12.83 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 136 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 12.83 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 136 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0