GPD2
Glycerol-3-phosphate dehydrogenase, mitochondrial
Protein Summary
The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jan 2010]
- ENST00000310454
- ENSP00000308610
- ENSG00000115159
- ENST00000409125
- ENSP00000386484
- ENST00000409674
- ENSP00000386425
- ENST00000409861
- ENSP00000386626
- ENST00000438166
- ENSP00000409708
- GDH2
- GPDM
- mGPDH
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor perturbation | 0.88 | ||
virus perturbation | 0.88 | ||
disease perturbation | 0.87 | ||
trait | 0.86 | ||
microRNA | 0.84 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 129.84 (req: < 5)
Gene RIFs: 12 (req: <= 3)
Antibodies: 250 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 129.84 (req: >= 5)
Gene RIFs: 12 (req: > 3)
Antibodies: 250 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 10
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0