You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
GPBP1L1
Vasculin-like protein 1

Protein Summary
Description
Possible transcription factor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000290795
  • ENSP00000290795
  • ENSG00000159592
  • ENST00000355105
  • ENSP00000347224

Symbol
  • SP192
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.82
transcription factor perturbation
0.74
histone modification site profile
0.71
gene perturbation
0.65
microRNA
0.63


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.22   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 50   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.22   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 50   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (59)
QRSL1
Tbio
Family:  Enzyme
Novelty:  0.0076614
p_int:  0.999999996
p_ni:  4e-9
Score:  0.185
Data Source:  BioPlex,STRINGDB
TC2N
Tbio
Novelty:  0.16223714
p_int:  0.999999336
p_ni:  2.06e-7
p_wrong:  4.58e-7
Score:  0.188
Data Source:  BioPlex,STRINGDB
PLCD3
Tbio
Family:  Enzyme
Novelty:  0.04749421
p_int:  0.999998083
p_ni:  0.000001917
Data Source:  BioPlex
KANSL2
Tbio
Novelty:  0.08741608
p_int:  0.9999706
p_ni:  0.000029381
p_wrong:  1.9e-8
Data Source:  BioPlex
NANOS2
Tbio
Novelty:  0.01489157
p_int:  0.999967893
p_ni:  0.000028164
p_wrong:  0.000003943
Score:  0.555
Data Source:  BioPlex,STRINGDB
PIP4K2A
Tbio
Family:  Kinase
Novelty:  0.01130885
p_int:  0.99996466
p_ni:  0.00003534
Data Source:  BioPlex
SNRPF
Tdark
Novelty:  0.17624854
p_int:  0.999960619
p_ni:  0.000039381
Data Source:  BioPlex
CNOT11
Tbio
Novelty:  0.01687183
p_int:  0.999950951
p_ni:  0.000049049
Score:  0.539
Data Source:  BioPlex,STRINGDB
AMPD2
Tchem
Family:  Enzyme
Novelty:  0.01510718
p_int:  0.999926344
p_ni:  0.000073655
p_wrong:  1e-9
Data Source:  BioPlex
ZBTB1
Tbio
Family:  TF
Novelty:  0.33667235
p_int:  0.999895183
p_ni:  0.000100582
p_wrong:  0.000004234
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (14)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte count
2
2
2
74.4
glomerular filtration rate
2
2
2
74.1
body height
2
2
2
72.4
platelet count
2
2
2
71.1
reticulocyte measurement
1
1
1
67.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte count
2
74.4
glomerular filtration rate
2
74.1
body height
2
72.4
platelet count
2
71.1
reticulocyte measurement
1
67.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
GC-rich promoter binding protein 1 like 1
VGNC:6848
456554
Macaque
GC-rich promoter binding protein 1 like 1
706690
Mouse
MGI:1924360
77110
Dog
GC-rich promoter binding protein 1 like 1
VGNC:41371
475372
Horse
GC-rich promoter binding protein 1 like 1
VGNC:18484
100052246
Species
Name
OMA
EggNOG
Inparanoid
Chimp
GC-rich promoter binding protein 1 like 1
Macaque
GC-rich promoter binding protein 1 like 1
Mouse
Dog
GC-rich promoter binding protein 1 like 1
Horse
GC-rich promoter binding protein 1 like 1
Publication Statistics
PubMed Score 1.22
PubMed score by year
PubTator Score 0.20
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title