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Tdark
GPATCH4
G patch domain-containing protein 4

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.59   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.59   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (166)
ZNF845
Tdark
Family:  TF
Novelty:  6.08968627
p_int:  0.999910069
p_ni:  0.00008105
p_wrong:  0.000008881
Data Source:  BioPlex
ZNF92
Tbio
Family:  TF
Novelty:  0.05724663
p_int:  0.998622448
p_ni:  0.001377552
Data Source:  BioPlex
NVL
Tbio
Family:  Enzyme
Novelty:  0.15855985
p_int:  0.994453391
p_ni:  0.005546609
Score:  0.217
Data Source:  BioPlex,STRINGDB
ZNF624
Tdark
Family:  TF
Novelty:  6.07364521
p_int:  0.992884093
p_ni:  0.006871666
p_wrong:  0.000244241
Data Source:  BioPlex
ZNF354A
Tbio
Family:  TF
Novelty:  0.04870859
p_int:  0.987082458
p_ni:  0.012901588
p_wrong:  0.000015954
Data Source:  BioPlex
MAK16
Tdark
Novelty:  0.07717917
p_int:  0.986230319
p_ni:  0.013769681
Score:  0.845
Data Source:  BioPlex,STRINGDB
TTF1
Tbio
Family:  TF
Novelty:  0.02558516
p_int:  0.985019472
p_ni:  0.014980528
Data Source:  BioPlex
RBM19
Tbio
Novelty:  0.15784228
p_int:  0.982265961
p_ni:  0.017734039
Score:  0.329
Data Source:  BioPlex,STRINGDB
DDX31
Tbio
Family:  Enzyme
Novelty:  2.84646195
p_int:  0.980028867
p_ni:  0.019971133
Score:  0.461
Data Source:  BioPlex,STRINGDB
NLE1
Tbio
Novelty:  0.03831535
p_int:  0.976188983
p_ni:  0.02380963
p_wrong:  0.000001387
Score:  0.301
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (13)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
leukocyte count
3
2
3
78.5
blood protein measurement
1
2
2
74.5
platelet crit
1
1
1
72.7
electrocardiography
1
1
7
70.9
neuroimaging measurement
10
1
10
46.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
leukocyte count
3
78.5
blood protein measurement
2
74.5
platelet crit
1
72.7
electrocardiography
7
70.9
neuroimaging measurement
10
46.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
G-patch domain containing 4
VGNC:11442
742166
Macaque
G-patch domain containing 4
718516
Mouse
MGI:1913864
66614
Rat
RGD:1311086
295228
Dog
G-patch domain containing 4
VGNC:41368
480121
Species
Name
OMA
EggNOG
Inparanoid
Chimp
G-patch domain containing 4
Macaque
G-patch domain containing 4
Mouse
Rat
Dog
G-patch domain containing 4
Publication Statistics
PubMed Score 1.59
PubMed score by year
PubTator Score 0.54
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title