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Tdark
GPATCH2L
G patch domain-containing protein 2-like

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000261530
  • ENSP00000261530
  • ENSG00000089916
  • ENST00000312858
  • ENSP00000323775
  • ENST00000556663
  • ENSP00000450657
  • ENST00000557263
  • ENSP00000451587
  • ENST00000621494
  • ENSP00000480608

Symbol
  • C14orf118
  • KIAA1152
  • C14orf118
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.73
small molecule perturbation
0.69
transcription factor binding site profile
0.69
transcription factor perturbation
0.68
transcription factor
0.65


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.73   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 22   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.73   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (43)
CSNK2A2
Tchem
Family:  Kinase
Novelty:  0.00231447
p_int:  0.999999999
p_ni:  1e-9
Score:  0.214
Data Source:  BioPlex,STRINGDB
TYMP
Tclin
Family:  Enzyme
Novelty:  0.0015906
p_int:  0.999818257
p_ni:  0.000181743
Score:  0.173
Data Source:  BioPlex,STRINGDB
CSNK2B
Tbio
Family:  Kinase
Novelty:  0.00152367
p_int:  0.999615781
p_ni:  9.27e-7
p_wrong:  0.000383292
Data Source:  BioPlex
PLBD1
Tdark
Family:  Enzyme
Novelty:  0.27639575
p_int:  0.999601553
p_ni:  0.000398447
Score:  0.157
Data Source:  BioPlex,STRINGDB
CSNK2A1
Tchem
Family:  Kinase
Novelty:  0.00187855
p_int:  0.997213565
p_ni:  0.002786435
Data Source:  BioPlex
A2ML1
Tbio
Novelty:  0.05923067
p_int:  0.987935426
p_ni:  0.012064568
p_wrong:  6e-9
Data Source:  BioPlex
SERPINB8
Tbio
Novelty:  0.03308357
p_int:  0.98196502
p_ni:  0.017927814
p_wrong:  0.000107166
Score:  0.173
Data Source:  BioPlex,STRINGDB
SERPINB2
Tbio
Novelty:  0.00204345
p_int:  0.980942267
p_ni:  0.019057399
p_wrong:  3.35e-7
Data Source:  BioPlex
JUP
Tbio
Novelty:  0.0081803
p_int:  0.980625237
p_ni:  0.019374763
Score:  0.171
Data Source:  BioPlex,STRINGDB
NEFH
Tbio
Novelty:  0.0013027
p_int:  0.9473226
p_ni:  0.052677398
p_wrong:  2e-9
Score:  0.169
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hemoglobin measurement
2
1
2
58.4
hematocrit
1
1
1
54.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hemoglobin measurement
2
58.4
hematocrit
1
54.4
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1917623
70373
Rat
RGD:1308907
314325
Dog
G-patch domain containing 2 like
VGNC:41366
480397
Horse
G-patch domain containing 2 like
VGNC:18479
100051827
Pig
G-patch domain containing 2 like
100153141
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
G-patch domain containing 2 like
Horse
G-patch domain containing 2 like
Pig
G-patch domain containing 2 like
Publication Statistics
PubMed Score 0.73
PubMed score by year
PubTator Score 0.20
PubTator score by year
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Related Publications
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PMID
Year
Title