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Tdark
GPANK1
G patch domain and ankyrin repeat-containing protein 1

Protein Summary
Description
This gene is located in a cluster of HLA-B-associated transcripts, which is included in the human major histocompatability complex III region. This gene encodes a protein which is thought to play a role in immunity. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000211377
  • ENSP00000211377
  • ENSG00000236011
  • ENST00000375893
  • ENSP00000365057
  • ENSG00000204438
  • ENST00000375895
  • ENSP00000365059
  • ENST00000375896
  • ENSP00000365060
  • ENST00000375900
  • ENSP00000365065
  • ENST00000375906
  • ENSP00000365071
  • ENST00000383434
  • ENSP00000372926
  • ENSG00000206408
  • ENST00000383436
  • ENSP00000372928
  • ENST00000400129
  • ENSP00000382994
  • ENST00000400134
  • ENSP00000382999
  • ENST00000400139
  • ENSP00000383005
  • ENST00000414528
  • ENSP00000389339
  • ENSG00000228605
  • ENST00000416384
  • ENSP00000401376
  • ENSG00000223932
  • ENST00000417890
  • ENSP00000415855
  • ENSG00000232312
  • ENST00000418502
  • ENSP00000412321
  • ENST00000422131
  • ENSP00000410690
  • ENST00000426326
  • ENSP00000398927
  • ENST00000427527
  • ENSP00000391604
  • ENST00000429266
  • ENSP00000412884
  • ENST00000433857
  • ENSP00000406895
  • ENST00000433880
  • ENSP00000401272
  • ENST00000439710
  • ENSP00000409206
  • ENST00000440777
  • ENSP00000399890
  • ENST00000447705
  • ENSP00000403829
  • ENST00000448091
  • ENSP00000411691
  • ENST00000449868
  • ENSP00000393567
  • ENST00000453746
  • ENSP00000390746
  • ENST00000453899
  • ENSP00000413662
  • ENST00000456191
  • ENSP00000401276
  • ENST00000457505
  • ENSP00000406507

Symbol
  • ANKRD59
  • BAT4
  • G5
  • GPATCH10
  • G5
  • BAT4
  • D6S54E
  • ANKRD59
  • GPATCH10
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.88
cellular component
0.72
disease
0.7
tissue sample
0.67
phenotype
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 61   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (35)
TTC19
Tbio
Novelty:  0.08251578
p_int:  0.999992068
p_ni:  0.000007932
Score:  0.21
Data Source:  BioPlex,STRINGDB
IL37
Tbio
Novelty:  0.00499186
p_int:  0.97835038
p_ni:  0.021022162
p_wrong:  0.000627458
Score:  0.199
Data Source:  BioPlex,STRINGDB
TGM1
Tchem
Family:  Enzyme
Novelty:  0.00103799
p_int:  0.830048205
p_ni:  0.169951795
Score:  0.234
Data Source:  BioPlex,STRINGDB
ALOX12B
Tbio
Family:  Enzyme
Novelty:  0.02778552
p_int:  0.798145824
p_ni:  0.201854176
Score:  0.28
Data Source:  BioPlex,STRINGDB
KPRP
Tdark
Novelty:  0.11744927
p_int:  0.764217823
p_ni:  0.234640654
p_wrong:  0.001141523
Score:  0.189
Data Source:  BioPlex,STRINGDB
HDGFL3
Tbio
Family:  Epigenetic
Novelty:  0.14292821
p_int:  0.751617718
p_ni:  0.000936626
p_wrong:  0.247445655
Score:  0.188
Data Source:  BioPlex,STRINGDB
APOM
Tbio
Novelty:  0.00505937
Score:  0.931
Data Source:  STRINGDB
ABHD16A
Tchem
Family:  Enzyme
Novelty:  0.04797219
Score:  0.883
Data Source:  STRINGDB
ZBTB12
Tbio
Family:  TF
Novelty:  0.15640131
Score:  0.804
Data Source:  STRINGDB
PRRC2A
Tbio
Novelty:  0.01493149
Score:  0.794
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (516)
Items per page:
1 – 5 of 516
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
3
0
3
96.3
1
3
0
3
96.3
1
3
0
3
96.3
1
3
0
3
96.3
1
3
0
3
96.3
Items per page:
1 – 5 of 516
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
3
96.3
0
3
96.3
0
3
96.3
0
3
96.3
0
3
96.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2148975
81845
Rat
RGD:1303304
415064
Dog
G-patch domain and ankyrin repeats 1
VGNC:41361
481714
Horse
G-patch domain and ankyrin repeats 1
VGNC:18472
100058617
Opossum
G-patch domain and ankyrin repeats 1
100025049
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
G-patch domain and ankyrin repeats 1
Horse
G-patch domain and ankyrin repeats 1
Opossum
G-patch domain and ankyrin repeats 1
Publication Statistics
PubMed Score 5.00
PubMed score by year
PubTator Score 76.07
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title