You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
GOLGA1
Golgin subfamily A member 1

Protein Summary
Description
Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking. The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein is associated with Sjogren's syndrome. [provided by RefSeq, Feb 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000373555
  • ENSP00000362656
  • ENSG00000136935

Symbol
  • golgin-97
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.97
histone modification site profile
0.92
microRNA
0.77
transcription factor binding site profile
0.77
disease perturbation
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.07   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 162   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.07   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 162   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (90)
SYCE1
Tbio
Novelty:  0.05038876
p_int:  0.999984915
p_ni:  1.4e-8
p_wrong:  0.000015071
Data Source:  BioPlex
GOLGA4
Tbio
Novelty:  0.01363253
Score:  0.986
Data Source:  STRINGDB
GCC2
Tbio
Novelty:  0.03809539
Score:  0.982
Data Source:  STRINGDB
GCC1
Tbio
Novelty:  0.0844824
Score:  0.981
Data Source:  STRINGDB
TGOLN2
Tbio
Novelty:  0.005107
Score:  0.976
Data Source:  STRINGDB
RAB6A
Tchem
Family:  Enzyme
Novelty:  0.00546034
Score:  0.974
Data Source:  STRINGDB
VTI1A
Tbio
Novelty:  0.04616617
Score:  0.973
Data Source:  STRINGDB
ARL1
Tbio
Family:  Enzyme
Novelty:  0.29930049
Score:  0.969
Data Source:  STRINGDB
STX16
Tbio
Novelty:  0.02462523
Score:  0.959
Data Source:  STRINGDB
STX6
Tbio
Novelty:  0.01494028
Score:  0.958
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Intra-Golgi and retrograde Golgi-to-ER traffic (R-HSA-6811442)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Intra-Golgi and retrograde Golgi-to-ER traffic
Reactome
Membrane Trafficking
Reactome
Retrograde transport at the Trans-Golgi-Network
Reactome
Vesicle-mediated transport
Name
Explore in Pharos
Explore in Source
Intra-Golgi and retrograde Golgi-to-ER traffic
Membrane Trafficking
Retrograde transport at the Trans-Golgi-Network
Vesicle-mediated transport
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (6)
Find Similar Targets
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
CACAO
Traceable Author Statement (TAS)
Reactome
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
Ensembl
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
7.1
71.6
IGF-1 measurement
1
1
1
35
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
7.1
71.6
IGF-1 measurement
1
35
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
golgin A1
VGNC:4754
464730
Macaque
golgin A1 [Source:HGNC Symbol;Acc:HGNC:4424]
Mouse
MGI:1924149
76899
Rat
RGD:1311305
311919
Dog
golgin A1
VGNC:41338
480728
Species
Name
OMA
EggNOG
Inparanoid
Chimp
golgin A1
Macaque
golgin A1 [Source:HGNC Symbol;Acc:HGNC:4424]
Mouse
Rat
Dog
golgin A1
Publication Statistics
PubMed Score 33.07
PubMed score by year
PubTator Score 16.91
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title