Tdark GML Glycosyl-phosphatidylinositol-anchored molecule-like protein

Protein Summary

Description

May play a role in the apoptotic pathway or cell-cycle regulation induced by p53/TP53 after DNA damage.

Uniprot Accession IDs

• Q99445
• A0AVF6
• O00686
• O00731

Gene Name

• GML

Ensembl ID

• ENST00000220940
• ENSP00000220940
• ENSG00000104499

Symbol

• LY6DL
• LY6DL

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.66
tissue	0.66
disease perturbation	0.62
cell line	0.5
disease	0.49

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.98   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 47   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.98   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 47   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0