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Tbio
GMFG
Glia maturation factor gamma

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000597595
  • ENSP00000472249
  • ENSG00000130755

Symbol
  • GMF-GAMMA
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.93
transcription factor
0.68
PubMedID
0.65
molecular function
0.63
disease perturbation
0.62


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.43   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 192   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.43   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 192   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (51)
GMFB
Tbio
Novelty:  0.01531815
p_int:  0.999999923
p_ni:  5e-8
p_wrong:  2.7e-8
Data Source:  BioPlex
PRUNE1
Tchem
Novelty:  0.02136836
p_int:  0.999339566
p_ni:  0.000660434
Score:  0.34
Data Source:  BioPlex,STRINGDB
LANCL2
Tchem
Novelty:  0.06086418
p_int:  0.959013146
p_ni:  0.040946425
p_wrong:  0.000040429
Score:  0.309
Data Source:  BioPlex,STRINGDB
HSPA14
Tbio
Novelty:  0.01714625
p_int:  0.8526645
p_ni:  0.147329835
p_wrong:  0.000005665
Score:  0.199
Data Source:  BioPlex,STRINGDB
ACTR2
Tchem
Novelty:  0.00731489
Score:  0.877
Data Source:  STRINGDB
LAPTM5
Tbio
Novelty:  0.06809459
Score:  0.765
Data Source:  STRINGDB
CD53
Tbio
Novelty:  0.01722633
Score:  0.76
Data Source:  STRINGDB
HCLS1
Tbio
Novelty:  0.08304056
Score:  0.736
Data Source:  STRINGDB
ARHGDIB
Tbio
Novelty:  0.01139758
Score:  0.733
Data Source:  STRINGDB
CD52
Tclin
Novelty:  0.00142013
Score:  0.672
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Immune System (R-HSA-168256)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Immune System
Reactome
Innate Immune System
Reactome
Neutrophil degranulation
Name
Explore in Pharos
Explore in Source
Immune System
Innate Immune System
Neutrophil degranulation
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (13)
Find Similar Targets
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
ProtInc
Traceable Author Statement (TAS)
ProtInc
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
7
3
0
2.2
91.3
3
1
0
2.1
84.2
remission
3
1
0
2.1
84.2
neutrophil count
1
1
1
59
mitochondrial heteroplasmy measurement
1
1
1
56.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
2.2
91.3
0
2.1
84.2
remission
0
2.1
84.2
neutrophil count
1
59
mitochondrial heteroplasmy measurement
1
56.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
glia maturation factor gamma
VGNC:7480
456019
Macaque
glia maturation factor gamma
697397
Mouse
MGI:1927135
63986
Rat
RGD:620506
113940
Horse
glia maturation factor gamma
VGNC:18405
100064427
Species
Name
OMA
EggNOG
Inparanoid
Chimp
glia maturation factor gamma
Macaque
glia maturation factor gamma
Mouse
Rat
Horse
glia maturation factor gamma
Publication Statistics
PubMed Score 21.43
PubMed score by year
PubTator Score 8.48
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title