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Tbio
GLT8D2
Glycosyltransferase 8 domain-containing protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000360814
  • ENSP00000354053
  • ENSG00000120820
  • ENST00000546436
  • ENSP00000449750
  • ENST00000548660
  • ENSP00000447450

Symbol
  • GALA4A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.61
histone modification site profile
0.59
virus perturbation
0.55
tissue sample
0.53
tissue
0.52


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.27   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 130   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.27   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 130   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (49)
PSCA
Tbio
Novelty:  0.00323778
p_int:  0.999958753
p_ni:  0.000040889
p_wrong:  3.58e-7
Data Source:  BioPlex
CHRNA3
Tclin
Family:  IC
Novelty:  0.00659767
p_int:  0.999579184
p_ni:  0.000420812
p_wrong:  4e-9
Data Source:  BioPlex
CHRNB4
Tclin
Family:  IC
Novelty:  0.01151716
p_int:  0.999564623
p_ni:  0.00043236
p_wrong:  0.000003017
Data Source:  BioPlex
FUT1
Tbio
Family:  Enzyme
Novelty:  0.00597206
p_int:  0.998741657
p_ni:  0.000831545
p_wrong:  0.000426798
Score:  0.167
Data Source:  BioPlex,STRINGDB
MME
Tclin
Family:  Enzyme
Novelty:  0.00019144
p_int:  0.995822912
p_ni:  0.000605202
p_wrong:  0.003571886
Score:  0.175
Data Source:  BioPlex,STRINGDB
QSOX1
Tbio
Family:  Enzyme
Novelty:  0.02152583
p_int:  0.994746019
p_ni:  0.003266692
p_wrong:  0.001987289
Score:  0.201
Data Source:  BioPlex,STRINGDB
MGAT4C
Tdark
Family:  Enzyme
Novelty:  0.19680806
p_int:  0.988226502
p_ni:  0.006722108
p_wrong:  0.005051391
Data Source:  BioPlex
RMND1
Tbio
Novelty:  0.06181833
p_int:  0.953659749
p_ni:  0.046338571
p_wrong:  0.00000168
Data Source:  BioPlex
EIF2AK3
Tchem
Family:  Kinase
Novelty:  0.00044559
p_int:  0.907006967
p_ni:  0.092993031
p_wrong:  2e-9
Score:  0.163
Data Source:  BioPlex,STRINGDB
OSBPL8
Tbio
Novelty:  0.06812531
p_int:  0.895250802
p_ni:  0.104749198
Score:  0.167
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
central corneal thickness
2
2
0
3.2
88.3
heel bone mineral density
2
2
2
65.7
vascular cell adhesion molecule-1 measurement
1
1
1
61
intraocular pressure measurement
1
1
1
57.3
corneal topography
1
1
1
42.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
central corneal thickness
0
3.2
88.3
heel bone mineral density
2
65.7
vascular cell adhesion molecule-1 measurement
1
61
intraocular pressure measurement
1
57.3
corneal topography
1
42.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
glycosyltransferase 8 domain containing 2
VGNC:5402
452189
Macaque
glycosyltransferase 8 domain containing 2
699937
Mouse
MGI:1922032
74782
Rat
RGD:1560432
366859
Dog
glycosyltransferase 8 domain containing 2
VGNC:41281
612239
Species
Name
OMA
EggNOG
Inparanoid
Chimp
glycosyltransferase 8 domain containing 2
Macaque
glycosyltransferase 8 domain containing 2
Mouse
Rat
Dog
glycosyltransferase 8 domain containing 2
Publication Statistics
PubMed Score 4.27
PubMed score by year
PubTator Score 0.50
PubTator score by year
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Related Publications
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PMID
Year
Title