GLS
Glutaminase kidney isoform, mitochondrial
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.99 | ||
transcription factor perturbation | 0.98 | ||
small molecule perturbation | 0.9 | ||
transcription factor binding site profile | 0.85 | ||
kinase perturbation | 0.84 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | Glutamate Neurotransmitter Release Cycle | ||||
Reactome | Glutamate and glutamine metabolism | ||||
Reactome | Metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
Glutamate Neurotransmitter Release Cycle | ||||
Glutamate and glutamine metabolism | ||||
Metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean platelet volume | 3 | 4 | 4 | 92.8 | |||||
reticulocyte count | 7 | 3 | 7 | 88.9 | |||||
3 | 2 | 0 | 1.3 | 87.4 | |||||
reticulocyte measurement | 3 | 2 | 3 | 79.2 | |||||
birth weight | 2 | 2 | 2 | 57.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean platelet volume | 4 | 92.8 | |||||
reticulocyte count | 7 | 88.9 | |||||
0 | 1.3 | 87.4 | |||||
reticulocyte measurement | 3 | 79.2 | |||||
birth weight | 2 | 57.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | glutaminase | VGNC:443 | 470606 | |||||
Mouse | MGI:95752 | 14660 | ||||||
Rat | RGD:2707 | 24398 | ||||||
Dog | glutaminase | VGNC:41276 | 488448 | |||||
Horse | glutaminase [Source:HGNC Symbol;Acc:HGNC:4331] | |||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | glutaminase | |||||
Mouse | ||||||
Rat | ||||||
Dog | glutaminase | |||||
Horse | glutaminase [Source:HGNC Symbol;Acc:HGNC:4331] | |||||
PMID | Year | Title |
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