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Tbio
GLG1
Golgi apparatus protein 1

Protein Summary
Description
Binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000205061
  • ENSP00000205061
  • ENSG00000090863
  • ENST00000422840
  • ENSP00000405984
  • ENST00000447066
  • ENSP00000406946

Symbol
  • CFR1
  • ESL1
  • MG160
  • CFR-1
  • ESL-1
  • MG160
  • MG-160
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.99
virus perturbation
0.97
kinase perturbation
0.96
transcription factor perturbation
0.96
transcription factor binding site profile
0.84


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 77.48   (req: < 5)
Gene RIFs: 12   (req: <= 3)
Antibodies: 297   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 77.48   (req: >= 5)
Gene RIFs: 12   (req: > 3)
Antibodies: 297   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (32)
SPPL2B
Tchem
Family:  Enzyme
Novelty:  0.0274774
p_int:  0.999498086
p_ni:  0.00050191
p_wrong:  5e-9
Score:  0.152
Data Source:  BioPlex,STRINGDB
FSD2
Tbio
Novelty:  0.1302271
p_int:  0.995181552
p_ni:  0.004818448
Data Source:  BioPlex
HADHA
Tbio
Novelty:  0.00385746
p_int:  0.979815841
p_ni:  0.020184159
Data Source:  BioPlex
PATE1
Tbio
Novelty:  0.0705075
p_int:  0.96659771
p_ni:  0.03340229
Data Source:  BioPlex
APOC3
Tclin
Novelty:  0.0009635
p_int:  0.941309432
p_ni:  0.058690568
Data Source:  BioPlex
UST
Tbio
Family:  Enzyme
Novelty:  0.03897672
p_int:  0.939788286
p_ni:  0.060211714
Score:  0.15
Data Source:  BioPlex,STRINGDB
DKK3
Tbio
Novelty:  0.00519275
p_int:  0.921287636
p_ni:  0.078712364
Data Source:  BioPlex
TFR2
Tbio
Family:  Enzyme
Novelty:  0.00480264
p_int:  0.920650225
p_ni:  0.079349775
Data Source:  BioPlex
EIF2B5
Tbio
Novelty:  0.0102209
p_int:  0.917754044
p_ni:  0.082245955
p_wrong:  1e-9
Data Source:  BioPlex
SCGB2A2
Tbio
Novelty:  0.01594053
p_int:  0.84826465
p_ni:  0.151735348
p_wrong:  2e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Cell surface interactions at the vascular wall (R-HSA-202733)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cell surface interactions at the vascular wall
Reactome
Hemostasis
Name
Explore in Pharos
Explore in Source
Cell surface interactions at the vascular wall
Hemostasis
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (15)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
2
2
2
83.2
monocyte percentage of leukocytes
2
1
2
80.5
neutrophil percentage of leukocytes
2
2
2
78.2
viral load
1
1
1
69.2
granulocyte percentage of myeloid white cells
1
1
1
64.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
2
83.2
monocyte percentage of leukocytes
2
80.5
neutrophil percentage of leukocytes
2
78.2
viral load
1
69.2
granulocyte percentage of myeloid white cells
1
64.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
golgi glycoprotein 1
VGNC:13709
454241
Macaque
golgi glycoprotein 1
710037
Mouse
MGI:104967
20340
Rat
RGD:69345
29476
Dog
golgi glycoprotein 1
VGNC:41255
479654
Species
Name
OMA
EggNOG
Inparanoid
Chimp
golgi glycoprotein 1
Macaque
golgi glycoprotein 1
Mouse
Rat
Dog
golgi glycoprotein 1
Publication Statistics
PubMed Score 77.48
PubMed score by year
PubTator Score 48.39
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title