Tbio GLCCI1 Glucocorticoid-induced transcript 1 protein

Protein Summary

Description

This gene encodes a protein of unknown function. Expression of this gene is induced by glucocorticoids and may be an early marker for glucocorticoid-induced apoptosis. Single nucleotide polymorphisms in this gene are associated with a decreased response to inhaled glucocorticoids in asthmatic patients. [provided by RefSeq, Feb 2012]

Uniprot Accession IDs

• Q86VQ1
• A4D103
• Q96FD0

Gene Name

• GLCCI1

Ensembl ID

• ENST00000223145
• ENSP00000223145
• ENSG00000106415

Symbol

• GCTR
• GIG18
• TSSN1
• FAM117C

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.99
transcription factor perturbation	0.94
kinase perturbation	0.76
transcription factor binding site profile	0.76
tissue	0.64

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.02   (req: < 5)

Gene RIFs: 24   (req: <= 3)

Antibodies: 174   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.02   (req: >= 5)

Gene RIFs: 24   (req: > 3)

Antibodies: 174   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0