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Tdark
GLB1L
Beta-galactosidase-1-like protein

Protein Summary
Description
Probable glycosyl hydrolase.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295759
  • ENSP00000295759
  • ENSG00000163521
  • ENST00000392089
  • ENSP00000375939
  • ENST00000409640
  • ENSP00000386354
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
pathway
0.96
tissue sample
0.74
protein domain
0.73
small molecule perturbation
0.6
histone modification site profile
0.54


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.47   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 63   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.47   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 63   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (38)
ERP29
Tbio
Novelty:  0.0132632
p_int:  0.99999974
p_ni:  1.73e-7
p_wrong:  8.8e-8
Score:  0.269
Data Source:  BioPlex,STRINGDB
SCGB2A1
Tbio
Novelty:  0.01902973
p_int:  0.999975952
p_ni:  0.00002404
p_wrong:  8e-9
Data Source:  BioPlex
RLN1
Tbio
Novelty:  0.03992636
p_int:  0.99993175
p_ni:  0.000068229
p_wrong:  2.1e-8
Data Source:  BioPlex
SCGB2A2
Tbio
Novelty:  0.01594053
p_int:  0.999831124
p_ni:  0.000168633
p_wrong:  2.43e-7
Data Source:  BioPlex
HYOU1
Tbio
Novelty:  0.00833649
p_int:  0.999696309
p_ni:  0.000302064
p_wrong:  0.000001627
Data Source:  BioPlex
LCN6
Tbio
Novelty:  0.11406686
p_int:  0.998079176
p_ni:  0.001693583
p_wrong:  0.000227241
Data Source:  BioPlex
LYPD2
Tdark
Novelty:  0.55307434
p_int:  0.997671777
p_ni:  0.000827735
p_wrong:  0.001500488
Data Source:  BioPlex
PSCA
Tbio
Novelty:  0.00323778
p_int:  0.997298023
p_ni:  0.002668485
p_wrong:  0.000033492
Data Source:  BioPlex
LEP
Tbio
Novelty:  0.00005295
p_int:  0.996501188
p_ni:  0.001306635
p_wrong:  0.002192178
Data Source:  BioPlex
DHFR2
Tbio
Family:  Enzyme
Novelty:  0.02374466
p_int:  0.992592793
p_ni:  0.006608785
p_wrong:  0.000798422
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (10)
Glycosaminoglycan metabolism (R-HSA-1630316)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 10
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Glycosaminoglycan metabolism
Reactome
Glycosphingolipid metabolism
Reactome
HS-GAG degradation
Reactome
Heparan sulfate/heparin (HS-GAG) metabolism
Reactome
Keratan sulfate degradation
Name
Explore in Pharos
Explore in Source
Glycosaminoglycan metabolism
Glycosphingolipid metabolism
HS-GAG degradation
Heparan sulfate/heparin (HS-GAG) metabolism
Keratan sulfate degradation
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (20)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
vitamin C measurement
1
1
1
92.7
reticulocyte count
6
3
8
87.3
reticulocyte measurement
3
2
5
84
mean reticulocyte volume
1
2
2
67.8
red blood cell distribution width
2
1
2
65.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
vitamin C measurement
1
92.7
reticulocyte count
8
87.3
reticulocyte measurement
5
84
mean reticulocyte volume
2
67.8
red blood cell distribution width
2
65.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
galactosidase beta 1 like
VGNC:441
470653
Macaque
galactosidase beta 1 like
702363
Mouse
MGI:1921827
74577
Rat
RGD:1309474
301525
Dog
galactosidase beta 1 like
VGNC:41250
478917
Species
Name
OMA
EggNOG
Inparanoid
Chimp
galactosidase beta 1 like
Macaque
galactosidase beta 1 like
Mouse
Rat
Dog
galactosidase beta 1 like
Publication Statistics
PubMed Score 2.47
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title