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Tbio
GIPC3
PDZ domain-containing protein GIPC3

Protein Summary
Description
Required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion. The protein encoded by this gene belongs to the GIPC family. Studies in mice suggest that this gene is required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion in the ear. Mutations in this gene are associated with autosomal recessive deafness. [provided by RefSeq, Dec 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000322315
  • ENSP00000319254
  • ENSG00000179855
  • ENST00000644452
  • ENSP00000493901

Symbol
  • C19orf64
  • DFNB15
  • DFNB72
  • DFNB95
  • C19orf64
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.68
tissue sample
0.66
microRNA
0.62
gene perturbation
0.53
tissue
0.49


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.72   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 140   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.72   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 140   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0