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Tbio
GIPC1
PDZ domain-containing protein GIPC1

Protein Summary
Description
May be involved in G protein-linked signaling. GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]).[supplied by OMIM, Apr 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000345425
  • ENSP00000340698
  • ENSG00000123159
  • ENST00000393028
  • ENSP00000376748
  • ENST00000393033
  • ENSP00000376753
  • ENST00000586027
  • ENSP00000466747
  • ENST00000591349
  • ENSP00000467077

Symbol
  • C19orf3
  • GIPC
  • RGS19IP1
  • NIP
  • GIPC
  • IIP-1
  • TIP-2
  • SEMCAP
  • C19orf3
  • Hs.6454
  • GLUT1CBP
  • RGS19IP1
  • SYNECTIN
  • SYNECTIIN
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.9
biological process
0.78
disease perturbation
0.68
tissue
0.68
cellular component
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 178.1   (req: < 5)
Gene RIFs: 32   (req: <= 3)
Antibodies: 263   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 178.1   (req: >= 5)
Gene RIFs: 32   (req: > 3)
Antibodies: 263   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 17
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0