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Tdark
GINM1
Glycoprotein integral membrane protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000367419
  • ENSP00000356389
  • ENSG00000055211

Symbol
  • C6orf72
  • C6orf72
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.98
histone modification site profile
0.89
kinase perturbation
0.76
disease perturbation
0.74
cellular component
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.28   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 46   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.28   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 46   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (49)
PLEKHA5
Tbio
Novelty:  0.11245799
p_int:  0.999999963
p_ni:  1.2e-8
p_wrong:  2.5e-8
Score:  0.169
Data Source:  BioPlex,STRINGDB
ITGB8
Tbio
Novelty:  0.01564348
p_int:  0.999996842
p_ni:  0.000003152
p_wrong:  6e-9
Data Source:  BioPlex
HS3ST2
Tbio
Family:  Enzyme
Novelty:  0.0611326
p_int:  0.999990545
p_ni:  0.000009455
Data Source:  BioPlex
CSGALNACT2
Tbio
Family:  Enzyme
Novelty:  0.0770692
p_int:  0.999982586
p_ni:  0.000017414
Data Source:  BioPlex
GLCE
Tbio
Family:  Enzyme
Novelty:  0.0497423
p_int:  0.999972125
p_ni:  0.00002787
p_wrong:  4e-9
Score:  0.183
Data Source:  BioPlex,STRINGDB
PCDHGA5
Tdark
Novelty:  2.13631603
p_int:  0.999966748
p_ni:  0.000033237
p_wrong:  1.5e-8
Data Source:  BioPlex
NMU
Tbio
Novelty:  0.00326109
p_int:  0.999887578
p_ni:  0.000076846
p_wrong:  0.000035576
Data Source:  BioPlex
CANT1
Tbio
Family:  Enzyme
Novelty:  0.02640333
p_int:  0.999846468
p_ni:  0.000153532
Data Source:  BioPlex
MPPE1
Tbio
Family:  Enzyme
Novelty:  0.16027847
p_int:  0.999712957
p_ni:  0.000222004
p_wrong:  0.000065039
Data Source:  BioPlex
SMOC1
Tbio
Novelty:  0.03819681
p_int:  0.999553178
p_ni:  0.000446821
p_wrong:  1e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Dupuytren Contracture
1
1
0
1.2
68.8
eosinophil count
2
2
2
58.2
brain stem volume measurement
1
1
0
6.7
49.5
eosinophil percentage of leukocytes
1
1
1
49.5
1
1
0
1.1
31.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Dupuytren Contracture
0
1.2
68.8
eosinophil count
2
58.2
brain stem volume measurement
0
6.7
49.5
eosinophil percentage of leukocytes
1
49.5
0
1.1
31.4
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
glycoprotein integral membrane 1
VGNC:2839
748369
Macaque
glycoprotein integral membrane 1
696511
Mouse
MGI:2384905
215751
Rat
RGD:1309759
361448
Dog
glycoprotein integral membrane 1
VGNC:53719
476239
Species
Name
OMA
EggNOG
Inparanoid
Chimp
glycoprotein integral membrane 1
Macaque
glycoprotein integral membrane 1
Mouse
Rat
Dog
glycoprotein integral membrane 1
Publication Statistics
PubMed Score 1.28
PubMed score by year
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Related Publications
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PMID
Year
Title