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Tbio
GGNBP2
Gametogenetin-binding protein 2

Protein Summary
Description
May be involved in spermatogenesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000613102
  • ENSP00000478220
  • ENSG00000278311
  • ENST00000621686
  • ENSP00000478954
  • ENSG00000275099

Symbol
  • LCRG1
  • LZK1
  • ZNF403
  • DIF3
  • LZK1
  • DIF-3
  • LCRG1
  • ZFP403
  • ZNF403
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.89
virus perturbation
0.88
disease perturbation
0.87
transcription factor
0.86
kinase perturbation
0.81


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 37.06   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 92   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 37.06   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 92   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (33)
PAK4
Tchem
Family:  Kinase
Novelty:  0.0068821
p_int:  0.999633084
p_ni:  0.000004469
p_wrong:  0.000362447
Score:  0.514
Data Source:  BioPlex,STRINGDB
CNOT11
Tbio
Novelty:  0.01687183
p_int:  0.995741005
p_ni:  0.000001415
p_wrong:  0.004257579
Score:  0.189
Data Source:  BioPlex,STRINGDB
ZNF331
Tbio
Family:  TF
Novelty:  0.05976217
p_int:  0.990712864
p_ni:  0.000003254
p_wrong:  0.009283882
Score:  0.173
Data Source:  BioPlex,STRINGDB
ZNHIT3
Tbio
Novelty:  0.08389205
Score:  0.713
Data Source:  STRINGDB
GGN
Tbio
Novelty:  0.07712274
Score:  0.701
Data Source:  STRINGDB
MYO19
Tbio
Novelty:  0.13070371
Score:  0.684
Data Source:  STRINGDB
C17orf78
Tdark
Novelty:  4.29271752
Score:  0.649
Data Source:  STRINGDB
TADA2A
Tbio
Family:  TF
Novelty:  0.07665459
Score:  0.622
Data Source:  STRINGDB
DHRS11
Tbio
Family:  Enzyme
Novelty:  0.00352776
Score:  0.617
Data Source:  STRINGDB
MRM1
Tbio
Family:  Enzyme
Novelty:  0.08762499
Score:  0.607
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (11)
Find Similar Targets
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (40)
Items per page:
1 – 5 of 40
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
CCL4 measurement
1
4
4
97.9
CCL4 measurement
1
4
4
97.9
macrophage inflammatory protein 1b measurement
1
4
4
97.3
macrophage inflammatory protein 1b measurement
1
4
4
97.3
red blood cell distribution width
4
4
4
93.9
Items per page:
1 – 5 of 40
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
CCL4 measurement
4
97.9
CCL4 measurement
4
97.9
macrophage inflammatory protein 1b measurement
4
97.3
macrophage inflammatory protein 1b measurement
4
97.3
red blood cell distribution width
4
93.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
gametogenetin binding protein 2
713750
Mouse
MGI:2387356
217039
Rat
RGD:1302978
360584
Dog
gametogenetin binding protein 2
VGNC:41200
480594
Horse
gametogenetin binding protein 2
VGNC:18326
100057558
Species
Name
OMA
EggNOG
Inparanoid
Macaque
gametogenetin binding protein 2
Mouse
Rat
Dog
gametogenetin binding protein 2
Horse
gametogenetin binding protein 2
Publication Statistics
PubMed Score 37.06
PubMed score by year
PubTator Score 25.61
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title