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Tdark
GFOD2
Glucose-fructose oxidoreductase domain-containing protein 2

Protein Summary
Description
Promotes matrix assembly.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000268797
  • ENSP00000268797
  • ENSG00000141098
  • ENST00000602279
  • ENSP00000478260
  • ENST00000602496
  • ENSP00000473641
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.88
cell type or tissue
0.6
cell line
0.56
tissue sample
0.56
transcription factor binding site profile
0.53


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.71   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 164   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.71   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 164   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (39)
GFOD1
Tdark
Family:  Enzyme
Novelty:  0.35031766
p_int:  0.999999996
p_wrong:  3e-9
Score:  0.684
Data Source:  BioPlex,STRINGDB
NKIRAS2
Tbio
Family:  Enzyme
Novelty:  0.11182522
p_int:  0.999999989
p_ni:  7e-9
p_wrong:  4e-9
Score:  0.869
Data Source:  BioPlex,STRINGDB
TXLNA
Tbio
Novelty:  0.02549959
p_int:  0.909785589
p_ni:  0.000066898
p_wrong:  0.090147513
Score:  0.187
Data Source:  BioPlex,STRINGDB
UROC1
Tbio
Family:  Enzyme
Novelty:  0.08693484
Score:  0.738
Data Source:  STRINGDB
LRRC29
Tdark
Novelty:  1.92387854
Score:  0.622
Data Source:  STRINGDB
TBCCD1
Tbio
Novelty:  0.21991508
Score:  0.613
Data Source:  STRINGDB
DNAJB7
Tbio
Novelty:  0.00419878
Score:  0.549
Data Source:  STRINGDB
SPRYD7
Tdark
Novelty:  0.25334319
Score:  0.543
Data Source:  STRINGDB
TSNAXIP1
Tdark
Novelty:  0.50007311
Score:  0.543
Data Source:  STRINGDB
B4GALNT1
Tbio
Family:  Enzyme
Novelty:  0.01060447
Score:  0.541
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (17)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
5
4
6
96.1
hematocrit
4
3
4
83.1
hemoglobin measurement
3
2
3
80.7
lymphocyte count
3
2
3
79.6
educational attainment
1
2
2
74
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
6
96.1
hematocrit
4
83.1
hemoglobin measurement
3
80.7
lymphocyte count
3
79.6
educational attainment
2
74
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
glucose-fructose oxidoreductase domain containing 2
VGNC:5778
742587
Mouse
MGI:1917825
70575
Rat
RGD:1311198
307801
Dog
glucose-fructose oxidoreductase domain containing 2
VGNC:41186
100855778
Horse
glucose-fructose oxidoreductase domain containing 2
VGNC:18314
100147209
Species
Name
OMA
EggNOG
Inparanoid
Chimp
glucose-fructose oxidoreductase domain containing 2
Mouse
Rat
Dog
glucose-fructose oxidoreductase domain containing 2
Horse
glucose-fructose oxidoreductase domain containing 2
Publication Statistics
PubMed Score 2.71
PubMed score by year
PubTator Score 1.06
PubTator score by year
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Related Publications
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PMID
Year
Title