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Tdark
GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000379284
  • ENSP00000368586
  • ENSG00000145990
  • ENST00000379287
  • ENSP00000368589
  • ENST00000612338
  • ENSP00000479493

Symbol
  • C6orf114
  • ADG-90
  • C6orf114
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.86
microRNA
0.79
PubMedID
0.76
tissue sample
0.75
transcription factor
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.59   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 35   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.59   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 35   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (41)
NKIRAS2
Tbio
Family:  Enzyme
Novelty:  0.11182522
p_int:  1
Score:  0.828
Data Source:  BioPlex,STRINGDB
GFOD2
Tdark
Family:  Enzyme
Novelty:  0.45929342
p_int:  0.999999996
p_wrong:  3e-9
Score:  0.684
Data Source:  BioPlex,STRINGDB
RALGAPA1
Tbio
Family:  Enzyme
Novelty:  0.11591036
p_int:  0.999999994
p_ni:  6e-9
Score:  0.681
Data Source:  BioPlex,STRINGDB
RALGAPA2
Tdark
Family:  Enzyme
Novelty:  0.12467725
p_int:  0.99999998
p_ni:  2e-8
Score:  0.734
Data Source:  BioPlex,STRINGDB
RALGAPB
Tbio
Family:  Enzyme
Novelty:  0.31941838
p_int:  0.999999972
p_ni:  2.8e-8
Score:  0.534
Data Source:  BioPlex,STRINGDB
CARD10
Tbio
Family:  Enzyme
Novelty:  0.01960502
p_int:  0.99999062
p_ni:  5.2e-8
p_wrong:  0.000009327
Score:  0.209
Data Source:  BioPlex,STRINGDB
FBXO9
Tbio
Novelty:  0.2145394
p_int:  0.999989266
p_ni:  1.07e-7
p_wrong:  0.000010628
Score:  0.209
Data Source:  BioPlex,STRINGDB
ERC1
Tbio
Novelty:  0.01251
p_int:  0.999760784
p_ni:  0.000235534
p_wrong:  0.000003682
Score:  0.209
Data Source:  BioPlex,STRINGDB
BCAT1
Tchem
Family:  Enzyme
Novelty:  0.00616446
p_int:  0.996004112
p_ni:  0.003995888
Score:  0.191
Data Source:  BioPlex,STRINGDB
AGBL5
Tbio
Family:  Enzyme
Novelty:  0.05735805
p_int:  0.993786703
p_ni:  0.006211955
p_wrong:  0.000001341
Score:  0.209
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
2
2
2
64.8
hemoglobin measurement
2
2
2
53.2
lymphocyte percentage of leukocytes
1
1
1
28.8
self reported educational attainment
1
1
1
21.5
aspartate aminotransferase measurement
1
1
0
8.7
21.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
2
64.8
hemoglobin measurement
2
53.2
lymphocyte percentage of leukocytes
1
28.8
self reported educational attainment
1
21.5
aspartate aminotransferase measurement
0
8.7
21.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
glucose-fructose oxidoreductase domain containing 1
700607
Mouse
MGI:2145304
328232
Rat
RGD:1311507
306842
Dog
glucose-fructose oxidoreductase domain containing 1
VGNC:41185
488222
Opossum
glucose-fructose oxidoreductase domain containing 1
100019231
Species
Name
OMA
EggNOG
Inparanoid
Macaque
glucose-fructose oxidoreductase domain containing 1
Mouse
Rat
Dog
glucose-fructose oxidoreductase domain containing 1
Opossum
glucose-fructose oxidoreductase domain containing 1
Publication Statistics
PubMed Score 2.59
PubMed score by year
PubTator Score 1.06
PubTator score by year
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Related Publications
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PMID
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