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Tbio
GDA
Guanine deaminase

Protein Summary
Description
Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. This gene encodes an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000238018
  • ENSP00000238018
  • ENSG00000119125
  • ENST00000358399
  • ENSP00000351170
  • ENST00000475764
  • ENSP00000436619
  • ENST00000545168
  • ENSP00000437972

Symbol
  • KIAA1258
  • GAH
  • CYPIN
  • GUANASE
  • NEDASIN
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.79
small molecule perturbation
0.73
microRNA
0.66
cellular component
0.57
gene perturbation
0.57


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 79.4   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 254   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 79.4   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 254   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0