GCAT
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor perturbation | 0.99 | ||
disease perturbation | 0.9 | ||
protein domain | 0.85 | ||
virus perturbation | 0.72 | ||
cell type or tissue | 0.64 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism | ||||
Reactome | Metabolism of amino acids and derivatives | ||||
Reactome | Threonine catabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism | ||||
Metabolism of amino acids and derivatives | ||||
Threonine catabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Non-traceable Author Statement (NAS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
serum albumin measurement | 1 | 2 | 2 | 72.4 | |||||
sex hormone-binding globulin measurement | 4 | 2 | 4 | 69.8 | |||||
cup-to-disc ratio measurement | 2 | 2 | 2 | 67.9 | |||||
heel bone mineral density | 2 | 1 | 2 | 67.1 | |||||
intraocular pressure measurement | 4 | 3 | 5 | 67.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
serum albumin measurement | 2 | 72.4 | |||||
sex hormone-binding globulin measurement | 4 | 69.8 | |||||
cup-to-disc ratio measurement | 2 | 67.9 | |||||
heel bone mineral density | 2 | 67.1 | |||||
intraocular pressure measurement | 5 | 67.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | glycine C-acetyltransferase | VGNC:5265 | 458820 | |||||
Macaque | glycine C-acetyltransferase | 698811 | ||||||
Mouse | MGI:1349389 | 26912 | ||||||
Rat | RGD:1307291 | 366959 | ||||||
Dog | glycine C-acetyltransferase | VGNC:41138 | 481262 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | glycine C-acetyltransferase | |||||
Macaque | glycine C-acetyltransferase | |||||
Mouse | ||||||
Rat | ||||||
Dog | glycine C-acetyltransferase | |||||
PMID | Year | Title |
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