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Tbio
GATAD2A
Transcriptional repressor p66-alpha

Protein Summary
Description
Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2B.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000358713
  • ENSP00000351552
  • ENSG00000167491
  • ENST00000360315
  • ENSP00000353463
  • ENST00000404158
  • ENSP00000384899

Symbol
  • p66alpha
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein complex
1
disease perturbation
0.97
transcription factor binding site profile
0.9
kinase perturbation
0.88
virus perturbation
0.88


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.03   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 203   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.03   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 203   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0