GATA2
Endothelial transcription factor GATA-2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
transcription factor perturbation | 0.98 | ||
molecular function | 0.96 | ||
PubMedID | 0.96 | ||
disease perturbation | 0.74 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Developmental Biology | ||||
Reactome | Factors involved in megakaryocyte development and platelet production | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | Hemostasis | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Developmental Biology | ||||
Factors involved in megakaryocyte development and platelet production | ||||
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
Hemostasis | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
monocyte percentage of leukocytes | 2 | 6 | 6 | 98.9 | |||||
eosinophil count | 4 | 4 | 3 | 9.4 | 97 | ||||
neutrophil count | 2 | 3 | 3 | 95.6 | |||||
lymphocyte percentage of leukocytes | 2 | 4 | 4 | 90.9 | |||||
monocyte count | 3 | 2 | 3 | 87.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
monocyte percentage of leukocytes | 6 | 98.9 | |||||
eosinophil count | 3 | 9.4 | 97 | ||||
neutrophil count | 3 | 95.6 | |||||
lymphocyte percentage of leukocytes | 4 | 90.9 | |||||
monocyte count | 3 | 87.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | GATA binding protein 2 | VGNC:1824 | 460672 | |||||
Macaque | GATA binding protein 2 | 705551 | ||||||
Mouse | MGI:95662 | 14461 | ||||||
Rat | RGD:2664 | 25159 | ||||||
Dog | GATA binding protein 2 | VGNC:41122 | 484626 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | GATA binding protein 2 | |||||
Macaque | GATA binding protein 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | GATA binding protein 2 | |||||
PMID | Year | Title |
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