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Tbio
GALNT17
Polypeptide N-acetylgalactosaminyltransferase 17

Protein Summary
Description
May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. This gene encodes an N-acetylgalactosaminyltransferase. This gene is located centromeric to the common deleted region in Williams-Beuren syndrome (WBS), a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. This protein may play a role in membrane trafficking. [provided by RefSeq, Jan 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000333538
  • ENSP00000329654
  • ENSG00000185274

Symbol
  • WBSCR17
  • GALNT16
  • GALNT20
  • GALNTL3
  • WBSCR17
  • GALNACT17
  • GalNAc-T17
  • GalNAc-T19
  • GalNAc-T5L
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.09   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 100   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.09   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 100   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (64)
C1GALT1
Tbio
Family:  Enzyme
Novelty:  0.01191596
Score:  0.908
Data Source:  STRINGDB
MUC1
Tchem
Novelty:  0.00024203
Score:  0.906
Data Source:  STRINGDB
MUC16
Tbio
Novelty:  0.00444587
Score:  0.902
Data Source:  STRINGDB
MUC3A
Tbio
Novelty:  0.0576775
Score:  0.9
Data Source:  STRINGDB
MUC17
Tbio
Novelty:  0.03624836
Score:  0.9
Data Source:  STRINGDB
MUC6
Tbio
Novelty:  0.00304872
Score:  0.9
Data Source:  STRINGDB
MUCL1
Tbio
Novelty:  0.05915667
Score:  0.9
Data Source:  STRINGDB
MUC20
Tbio
Novelty:  0.04645313
Score:  0.9
Data Source:  STRINGDB
MUC15
Tbio
Novelty:  0.02213624
Score:  0.9
Data Source:  STRINGDB
MUC5AC
Tbio
Novelty:  0.00074159
Score:  0.9
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (7)
Metabolism of proteins (R-HSA-392499)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
O-linked glycosylation
Reactome
O-linked glycosylation of mucins
Reactome
Post-translational protein modification
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
O-linked glycosylation
O-linked glycosylation of mucins
Post-translational protein modification
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (32)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
1
7
7
77.8
lymphocyte count
2
2
2
71.4
body weight
2
2
2
69.2
self reported educational attainment
1
3
3
68.7
body mass index
3
2
3
66.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
7
77.8
lymphocyte count
2
71.4
body weight
2
69.2
self reported educational attainment
3
68.7
body mass index
3
66.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
polypeptide N-acetylgalactosaminyltransferase 17
463458
Macaque
polypeptide N-acetylgalactosaminyltransferase 17
695207
Mouse
MGI:2137594
212996
Chicken
Williams-Beuren syndrome chromosome region 17
CGNC:765
417480
Species
Name
OMA
EggNOG
Inparanoid
Chimp
polypeptide N-acetylgalactosaminyltransferase 17
Macaque
polypeptide N-acetylgalactosaminyltransferase 17
Mouse
Chicken
Williams-Beuren syndrome chromosome region 17
Publication Statistics
PubMed Score 11.09
PubMed score by year
PubTator Score 2.56
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title