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Tbio
GALNT16
Polypeptide N-acetylgalactosaminyltransferase 16

Protein Summary
Description
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000337827
  • ENSP00000336729
  • ENSG00000100626
  • ENST00000448469
  • ENSP00000402970
  • ENST00000553471
  • ENSP00000451420
  • ENST00000553669
  • ENSP00000451200

Symbol
  • GALNTL1
  • KIAA1130
  • GALNTL1
  • GALNACT16
  • GalNAc-T16
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.64
protein domain
0.58
tissue sample
0.57
cellular component
0.55
microRNA
0.54


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.37   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 63   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.37   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 63   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (76)
PRPSAP2
Tbio
Family:  Enzyme
Novelty:  0.12017454
p_int:  0.999986949
p_ni:  0.000012887
p_wrong:  1.64e-7
Data Source:  BioPlex
REEP5
Tbio
Novelty:  0.00160455
p_int:  0.999972951
p_ni:  0.000027049
Score:  0.162
Data Source:  BioPlex,STRINGDB
SCPEP1
Tbio
Family:  Enzyme
Novelty:  0.08603794
p_int:  0.999923622
p_ni:  0.000003586
p_wrong:  0.000072791
Data Source:  BioPlex
PEX19
Tbio
Novelty:  0.00605342
p_int:  0.999773754
p_ni:  0.000226246
Score:  0.202
Data Source:  BioPlex,STRINGDB
ARHGAP17
Tbio
Family:  Enzyme
Novelty:  0.06611987
p_int:  0.997239598
p_ni:  0.002760399
p_wrong:  3e-9
Score:  0.243
Data Source:  BioPlex,STRINGDB
IPO8
Tbio
Novelty:  0.00934966
p_int:  0.965270414
p_ni:  0.034729586
Score:  0.189
Data Source:  BioPlex,STRINGDB
GAPDHS
Tbio
Family:  Enzyme
Novelty:  0.00885959
p_int:  0.944763327
p_ni:  0.055236673
p_wrong:  1e-9
Data Source:  BioPlex
SLC39A11
Tbio
Family:  Transporter
Novelty:  0.09770302
p_int:  0.918570202
p_ni:  0.081429798
Score:  0.439
Data Source:  BioPlex,STRINGDB
RMND1
Tbio
Novelty:  0.06181833
p_int:  0.835602882
p_ni:  0.164397095
p_wrong:  2.3e-8
Data Source:  BioPlex
C1GALT1
Tbio
Family:  Enzyme
Novelty:  0.01191596
Score:  0.956
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (8)
Metabolism of proteins (R-HSA-392499)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
O-linked glycosylation
Reactome
O-linked glycosylation of mucins
Reactome
Post-translational protein modification
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
O-linked glycosylation
O-linked glycosylation of mucins
Post-translational protein modification
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (19)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
2
2
2
89
myeloid white cell count
1
1
1
70.2
neutrophil percentage of leukocytes
1
1
1
68.6
self reported educational attainment
2
2
2
65.7
leukocyte count
1
1
1
61.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
2
89
myeloid white cell count
1
70.2
neutrophil percentage of leukocytes
1
68.6
self reported educational attainment
2
65.7
leukocyte count
1
61.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
polypeptide N-acetylgalactosaminyltransferase 16
VGNC:48896
467488
Macaque
polypeptide N-acetylgalactosaminyltransferase 16
714574
Mouse
MGI:1917754
108760
Rat
RGD:1310202
362760
Dog
polypeptide N-acetylgalactosaminyltransferase 16
VGNC:41091
480370
Species
Name
OMA
EggNOG
Inparanoid
Chimp
polypeptide N-acetylgalactosaminyltransferase 16
Macaque
polypeptide N-acetylgalactosaminyltransferase 16
Mouse
Rat
Dog
polypeptide N-acetylgalactosaminyltransferase 16
Publication Statistics
PubMed Score 3.37
PubMed score by year
PubTator Score 1.14
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title