GAB2
GRB2-associated-binding protein 2
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
hub protein | 0.96 | ||
kinase | 0.92 | ||
transcription factor binding site profile | 0.9 | ||
transcription factor | 0.77 | ||
histone modification site profile | 0.76 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Axon guidance | ||||
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | Developmental Biology | ||||
Reactome | Disease | ||||
Reactome | Diseases of signal transduction | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Axon guidance | ||||
Cytokine Signaling in Immune system | ||||
Developmental Biology | ||||
Disease | ||||
Diseases of signal transduction | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
glomerular filtration rate | 3 | 2 | 3 | 82.9 | |||||
hair color | 2 | 1 | 0 | 1.1 | 76.4 | ||||
aspartate aminotransferase measurement | 1 | 1 | 0 | 10 | 75.7 | ||||
total cholesterol measurement | 2 | 2 | 2 | 74 | |||||
age at menarche | 2 | 2 | 1 | 3.1 | 66.6 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
glomerular filtration rate | 3 | 82.9 | |||||
hair color | 0 | 1.1 | 76.4 | ||||
aspartate aminotransferase measurement | 0 | 10 | 75.7 | ||||
total cholesterol measurement | 2 | 74 | |||||
age at menarche | 1 | 3.1 | 66.6 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | GRB2 associated binding protein 2 | VGNC:11785 | 748918 | |||||
Macaque | GRB2 associated binding protein 2 | 700197 | ||||||
Mouse | MGI:1333854 | 14389 | ||||||
Rat | RGD:621367 | 84477 | ||||||
Horse | GRB2 associated binding protein 2 | 100062877 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | GRB2 associated binding protein 2 | |||||
Macaque | GRB2 associated binding protein 2 | |||||
Mouse | ||||||
Rat | ||||||
Horse | GRB2 associated binding protein 2 | |||||
PMID | Year | Title |
---|