You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
FUT4
Alpha-(1,3)-fucosyltransferase 4

Protein Summary
Description
May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens. The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). [provided by RefSeq, Jan 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000358752
  • ENSP00000351602
  • ENSG00000196371

Symbol
  • ELFT
  • FCT3A
  • LeX
  • CD15
  • ELFT
  • FCT3A
  • FUTIV
  • SSEA-1
  • FUC-TIV
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.98
PubMedID
0.85
virus perturbation
0.83
disease perturbation
0.68
cellular component
0.67


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1807.43   (req: < 5)
Gene RIFs: 67   (req: <= 3)
Antibodies: 1626   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1807.43   (req: >= 5)
Gene RIFs: 67   (req: > 3)
Antibodies: 1626   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0