You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
FUT11
Alpha-(1,3)-fucosyltransferase 11

Protein Summary
Description
Probable fucosyltransferase.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372841
  • ENSP00000361932
  • ENSG00000196968
  • ENST00000394790
  • ENSP00000378270

Symbol
  • FUCTXI
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.76
cellular component
0.74
transcription factor perturbation
0.68
tissue sample
0.67
transcription factor binding site profile
0.64


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.64   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 129   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.64   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 129   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (57)
PRG3
Tbio
Novelty:  0.09431986
p_int:  0.999865055
p_ni:  0.000134945
Data Source:  BioPlex
TAZ
Tbio
Novelty:  0.00372301
p_int:  0.999732802
p_ni:  0.000266178
p_wrong:  0.00000102
Data Source:  BioPlex
PRG2
Tbio
Novelty:  0.00548995
p_int:  0.999223775
p_ni:  0.000776208
p_wrong:  1.7e-8
Data Source:  BioPlex
PTPRK
Tbio
Family:  Enzyme
Novelty:  0.03149943
p_int:  0.998976002
p_ni:  0.001023997
Data Source:  BioPlex
PLAUR
Tchem
Family:  Enzyme
Novelty:  0.00087642
p_int:  0.998902971
p_ni:  0.001097021
p_wrong:  8e-9
Data Source:  BioPlex
TMEM25
Tdark
Novelty:  0.35505784
p_int:  0.998688656
p_ni:  0.001311323
p_wrong:  2.1e-8
Data Source:  BioPlex
DNASE2B
Tbio
Family:  Enzyme
Novelty:  0.02506932
p_int:  0.998669658
p_ni:  0.001330217
p_wrong:  1.25e-7
Data Source:  BioPlex
INSL5
Tbio
Novelty:  0.04351334
p_int:  0.998413438
p_ni:  0.001583058
p_wrong:  0.000003504
Data Source:  BioPlex
SLAMF1
Tbio
Novelty:  0.00112892
p_int:  0.997609393
p_ni:  0.002390344
p_wrong:  2.62e-7
Data Source:  BioPlex
SUSD4
Tbio
Novelty:  0.22201938
p_int:  0.996511578
p_ni:  0.003488421
p_wrong:  1e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (5)
Blood group systems biosynthesis (R-HSA-9033658)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Blood group systems biosynthesis
Reactome
Lewis blood group biosynthesis
Reactome
Metabolism
Reactome
Metabolism of carbohydrates
Name
Explore in Pharos
Explore in Source
Blood group systems biosynthesis
Lewis blood group biosynthesis
Metabolism
Metabolism of carbohydrates
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (13)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
forced expiratory volume
1
2
2
76.4
C-reactive protein measurement
2
2
2
68.5
FEV/FEC ratio
1
2
2
63.6
1
1
0
1.1
61.4
serum gamma-glutamyl transferase measurement
1
1
1
56.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
forced expiratory volume
2
76.4
C-reactive protein measurement
2
68.5
FEV/FEC ratio
2
63.6
0
1.1
61.4
serum gamma-glutamyl transferase measurement
1
56.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
fucosyltransferase 11
VGNC:9729
450526
Macaque
fucosyltransferase 11
706552
Mouse
MGI:1920318
73068
Rat
RGD:628731
286971
Dog
fucosyltransferase 11
VGNC:41013
100856055
Species
Name
OMA
EggNOG
Inparanoid
Chimp
fucosyltransferase 11
Macaque
fucosyltransferase 11
Mouse
Rat
Dog
fucosyltransferase 11
Publication Statistics
PubMed Score 6.64
PubMed score by year
PubTator Score 48.25
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title