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Tbio
FUNDC2
FUN14 domain-containing protein 2

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.08   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 85   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.08   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 85   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (29)
SEC11C
Tdark
Family:  Enzyme
Novelty:  0.19577003
p_int:  0.999988523
p_ni:  0.000011472
p_wrong:  4e-9
Score:  0.164
Data Source:  BioPlex,STRINGDB
FPR2
Tchem
Family:  GPCR
Novelty:  0.00228744
p_int:  0.99996438
p_ni:  0.000035608
p_wrong:  1.2e-8
Data Source:  BioPlex
FAF2
Tbio
Novelty:  0.03048598
p_int:  0.999644783
p_ni:  0.000355217
Data Source:  BioPlex
C20orf141
Tdark
Novelty:  7
p_int:  0.999389562
p_ni:  0.000502248
p_wrong:  0.00010819
Data Source:  BioPlex
METTL9
Tdark
Family:  Enzyme
Novelty:  0.20589257
p_int:  0.998949275
p_ni:  0.000857955
p_wrong:  0.00019277
Data Source:  BioPlex
TMEM128
Tdark
Novelty:  5.15874803
p_int:  0.997680417
p_ni:  0.00174486
p_wrong:  0.000574723
Score:  0.165
Data Source:  BioPlex,STRINGDB
FUNDC1
Tbio
Novelty:  0.02333176
p_int:  0.997508764
p_ni:  7e-8
p_wrong:  0.002491166
Score:  0.527
Data Source:  BioPlex,STRINGDB
DHCR24
Tchem
Family:  Enzyme
Novelty:  0.00480473
p_int:  0.991709533
p_ni:  0.006268804
p_wrong:  0.002021663
Score:  0.23
Data Source:  BioPlex,STRINGDB
DNAJC7
Tbio
Novelty:  0.02133191
p_int:  0.813044652
p_ni:  0.00018012
p_wrong:  0.186775228
Data Source:  BioPlex
NEDD8
Tchem
Novelty:  0.00305343
Score:  0.726
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.1
53.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.1
53.3
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
FUN14 domain containing 2
574259
Mouse
MGI:1914641
67391
Dog
FUN14 domain containing 2
VGNC:41008
613014
Horse
FUN14 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24925]
Cow
FUN14 domain containing 2
VGNC:29144
281813
Species
Name
OMA
EggNOG
Inparanoid
Macaque
FUN14 domain containing 2
Mouse
Dog
FUN14 domain containing 2
Horse
FUN14 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24925]
Cow
FUN14 domain containing 2
Publication Statistics
PubMed Score 11.08
PubMed score by year
PubTator Score 3.20
PubTator score by year
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Related Publications
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PMID
Year
Title