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Tbio
FOXR2
Forkhead box protein R2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000339140
  • ENSP00000427329
  • ENSG00000189299

Symbol
  • FOXN6
  • FOXN6
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.71
microRNA
0.58
cell line
0.5
biological process
0.46
cell type or tissue
0.41


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.95   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 106   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.95   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 106   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (63)
MYC
Tchem
Family:  TF
Novelty:  0.00005734
p_int:  0.999999833
p_ni:  5.4e-8
p_wrong:  1.13e-7
Score:  0.859
Data Source:  BioPlex,STRINGDB
KAT5
Tchem
Family:  Epigenetic
Novelty:  0.00368348
p_int:  0.999999798
p_ni:  2.02e-7
Score:  0.82
Data Source:  BioPlex,STRINGDB
ING3
Tbio
Family:  Epigenetic
Novelty:  0.01696145
p_int:  0.999999756
p_ni:  2.43e-7
p_wrong:  1e-9
Score:  0.697
Data Source:  BioPlex,STRINGDB
EPC1
Tbio
Novelty:  0.03216371
p_int:  0.999999679
p_ni:  3.21e-7
Score:  0.699
Data Source:  BioPlex,STRINGDB
EPC2
Tbio
Novelty:  0.02760809
p_int:  0.999999465
p_ni:  5.35e-7
Score:  0.699
Data Source:  BioPlex,STRINGDB
EP400
Tbio
Novelty:  0.02013098
p_int:  0.999998519
p_ni:  0.000001481
Score:  0.711
Data Source:  BioPlex,STRINGDB
ARNT
Tbio
Family:  TF
Novelty:  0.00183071
p_int:  0.999997203
p_ni:  0.000002797
Score:  0.179
Data Source:  BioPlex,STRINGDB
TRRAP
Tbio
Novelty:  0.01517245
p_int:  0.999997068
p_ni:  0.000002932
Score:  0.779
Data Source:  BioPlex,STRINGDB
MBTD1
Tbio
Family:  Epigenetic
Novelty:  0.11651052
p_int:  0.999993452
p_ni:  0.000006548
Score:  0.687
Data Source:  BioPlex,STRINGDB
MEAF6
Tbio
Novelty:  0.0914094
p_int:  0.999992539
p_ni:  0.000007456
p_wrong:  5e-9
Score:  0.728
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
1
1
1
46.4
mean corpuscular volume
1
1
1
0.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
1
46.4
mean corpuscular volume
1
0.2
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:3511682
436240
Rat
RGD:1564437
302583
Dog
forkhead box R2
VGNC:40970
100682939
Horse
forkhead box R2
VGNC:18118
100050330
Zebrafish
ZDB-GENE-070928-26
570997
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
forkhead box R2
Horse
forkhead box R2
Zebrafish
Publication Statistics
PubMed Score 30.95
PubMed score by year
PubTator Score 8.08
PubTator score by year
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Related Publications
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PMID
Year
Title