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Tbio
FOPNL
LisH domain-containing protein FOPNL

Protein Summary
Description
Involved in the biogenesis of cilia (PubMed:20551181). Required for the recruitement of PLK1 to centrosomes and S phase progression (PubMed:24018379).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000255759
  • ENSP00000255759
  • ENSG00000133393
  • ENST00000573968
  • ENSP00000460312
  • ENST00000622266
  • ENSP00000481290
  • ENSG00000276914
  • ENST00000631974
  • ENSP00000488488

Symbol
  • C16orf63
  • FOR20
  • PHSECRG2
  • FOR20
  • C16orf63
  • PHSECRG2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.74
transcription factor binding site profile
0.73
microRNA
0.69
cell type or tissue
0.67
tissue sample
0.63


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.01   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 44   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.01   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 44   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (41)
KIAA0753
Tdark
Novelty:  0.00878365
p_int:  0.999999978
p_ni:  3e-9
p_wrong:  1.9e-8
Score:  0.475
Data Source:  BioPlex,STRINGDB
OFD1
Tbio
Novelty:  0.01032841
p_int:  0.999999876
p_ni:  1.23e-7
p_wrong:  1e-9
Score:  0.798
Data Source:  BioPlex,STRINGDB
CRYGD
Tbio
Novelty:  0.00246109
p_int:  0.999988495
p_ni:  0.0000115
p_wrong:  5e-9
Data Source:  BioPlex
TYW1
Tbio
Family:  Enzyme
Novelty:  0.05117274
p_int:  0.961793989
p_ni:  0.038206011
Data Source:  BioPlex
LIN7B
Tbio
Novelty:  0.12689192
p_int:  0.88374176
p_ni:  0.001211599
p_wrong:  0.115046642
Data Source:  BioPlex
C16orf45
Tbio
Novelty:  0.00913059
Score:  0.795
Data Source:  STRINGDB
MARF1
Tdark
Novelty:  0.07787954
Score:  0.785
Data Source:  STRINGDB
ISY1
Tdark
Novelty:  1.68602768
Score:  0.737
Data Source:  STRINGDB
CCDC61
Tdark
Novelty:  0.78730217
Score:  0.691
Data Source:  STRINGDB
MPV17L
Tbio
Novelty:  0.13698206
Score:  0.681
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (8)
Find Similar Targets
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
HPA
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (20)
Items per page:
1 – 5 of 20
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Ischemic stroke
1
1
0
4.6
70.8
Ischemic stroke
1
1
0
4.6
70.8
overall survival
1
1
0
1.9
54.1
1
1
0
1.9
54.1
overall survival
1
1
0
1.9
54.1
Items per page:
1 – 5 of 20
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Ischemic stroke
0
4.6
70.8
Ischemic stroke
0
4.6
70.8
overall survival
0
1.9
54.1
0
1.9
54.1
overall survival
0
1.9
54.1
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1913336
66086
Rat
RGD:1305823
360461
Dog
FGFR1OP N-terminal like
VGNC:40939
100684094
Cow
FGFR1OP N-terminal like
VGNC:29072
782821
Opossum
FGFR1OP N-terminal like
100023290
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
FGFR1OP N-terminal like
Cow
FGFR1OP N-terminal like
Opossum
FGFR1OP N-terminal like
Publication Statistics
PubMed Score 30.01
PubMed score by year
PubTator Score 6.83
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title