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Tbio
FNDC3A
Fibronectin type-III domain-containing protein 3A

Protein Summary
Description
Mediates spermatid-Sertoli adhesion during spermatogenesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000398316
  • ENSP00000381362
  • ENSG00000102531
  • ENST00000492622
  • ENSP00000417257
  • ENST00000541916
  • ENSP00000441831

Symbol
  • FNDC3
  • HUGO
  • KIAA0970
  • HUGO
  • FNDC3
  • bA203I16.1
  • bA203I16.5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.88
microRNA
0.85
ligand (protein) perturbation
0.83
transcription factor
0.76
transcription factor perturbation
0.74


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.27   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 112   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.27   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 112   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (73)
TENT5A
Tbio
Novelty:  0.08412895
p_int:  0.999999932
p_ni:  6.2e-8
p_wrong:  5e-9
Score:  0.157
Data Source:  BioPlex,STRINGDB
ADCY9
Tbio
Family:  Enzyme
Novelty:  0.00744116
p_int:  0.999583337
p_ni:  0.000416663
Data Source:  BioPlex
FPR2
Tchem
Family:  GPCR
Novelty:  0.00228744
p_int:  0.999365057
p_ni:  0.000634803
p_wrong:  1.39e-7
Data Source:  BioPlex
SYT3
Tbio
Novelty:  0.02593006
p_int:  0.999160495
p_ni:  0.000839041
p_wrong:  4.64e-7
Score:  0.169
Data Source:  BioPlex,STRINGDB
IL27RA
Tbio
Novelty:  0.01348051
p_int:  0.99844804
p_ni:  0.00155196
Data Source:  BioPlex
CD1E
Tbio
Novelty:  0.00171622
p_int:  0.997920903
p_ni:  0.002079097
Data Source:  BioPlex
DLK1
Tchem
Novelty:  0.00212394
p_int:  0.980353905
p_ni:  0.019621568
p_wrong:  0.000024527
Data Source:  BioPlex
FADS3
Tbio
Family:  Enzyme
Novelty:  0.02899077
p_int:  0.971981188
p_ni:  0.02798997
p_wrong:  0.000028843
Data Source:  BioPlex
CLEC2D
Tbio
Novelty:  0.02501194
p_int:  0.971050967
p_ni:  0.028949024
p_wrong:  9e-9
Data Source:  BioPlex
PDGFRB
Tclin
Family:  Kinase
Novelty:  0.00074896
p_int:  0.947938887
p_ni:  0.052061113
Score:  0.179
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (12)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
apolipoprotein A 1 measurement
1
1
1
10.9
high density lipoprotein cholesterol measurement
1
1
1
6.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
apolipoprotein A 1 measurement
1
10.9
high density lipoprotein cholesterol measurement
1
6.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
fibronectin type III domain containing 3A
VGNC:13109
467356
Macaque
fibronectin type III domain containing 3A
705570
Mouse
MGI:1196463
319448
Rat
RGD:1304736
306022
Dog
fibronectin type III domain containing 3A
VGNC:40928
476914
Species
Name
OMA
EggNOG
Inparanoid
Chimp
fibronectin type III domain containing 3A
Macaque
fibronectin type III domain containing 3A
Mouse
Rat
Dog
fibronectin type III domain containing 3A
Publication Statistics
PubMed Score 19.27
PubMed score by year
PubTator Score 9.12
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title