FMNL1
Formin-like protein 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.92 | ||
ligand (protein) perturbation | 0.83 | ||
cellular component | 0.71 | ||
transcription factor | 0.69 | ||
co-expressed gene | 0.61 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | RHO GTPase Effectors | ||||
Reactome | RHO GTPases Activate Formins | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by Rho GTPases | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
RHO GTPase Effectors | ||||
RHO GTPases Activate Formins | ||||
Signal Transduction | ||||
Signaling by Rho GTPases | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 1 | 4 | 4 | 83.9 | |||||
appendicular lean mass | 2 | 1 | 2 | 80.4 | |||||
body height | 3 | 1 | 3 | 78 | |||||
myeloid white cell count | 1 | 1 | 1 | 67.1 | |||||
platelet crit | 1 | 1 | 1 | 66.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 4 | 83.9 | |||||
appendicular lean mass | 2 | 80.4 | |||||
body height | 3 | 78 | |||||
myeloid white cell count | 1 | 67.1 | |||||
platelet crit | 1 | 66.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | formin like 1 | VGNC:9283 | 736805 | |||||
Macaque | formin like 1 | 716211 | ||||||
Mouse | MGI:1888994 | 57778 | ||||||
Rat | RGD:1311042 | 287746 | ||||||
Dog | formin like 1 | VGNC:40914 | 490927 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | formin like 1 | |||||
Macaque | formin like 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | formin like 1 | |||||
PMID | Year | Title |
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