FMN1
Formin-1
Protein Summary
Plays a role in the formation of adherens junction and the polymerization of linear actin cables. This gene belongs to the formin homology family and encodes a protein that has a role in the formation of adherens junction and the polymerization of linear actin cables. The homologous gene in mouse is associated with limb deformity. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
- ENST00000320930
- ENSP00000325166
- ENSG00000248905
- ENST00000334528
- ENSP00000333950
- ENST00000558197
- ENSP00000452984
- ENST00000559047
- ENSP00000454047
- ENST00000616417
- ENSP00000479134
- ENST00000631469
- ENSP00000488866
- ENSG00000282513
- ENST00000631756
- ENSP00000488300
- ENST00000631811
- ENSP00000488198
- ENST00000632024
- ENSP00000488532
- ENST00000633316
- ENSP00000487643
- FMN
- LD
- LD
- FMN
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
virus perturbation | 0.94 | ||
microRNA | 0.87 | ||
trait | 0.86 | ||
histone modification site profile | 0.67 | ||
cell type or tissue | 0.66 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 975.46 (req: < 5)
Gene RIFs: 11 (req: <= 3)
Antibodies: 92 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 975.46 (req: >= 5)
Gene RIFs: 11 (req: > 3)
Antibodies: 92 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 11
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0