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Tdark
FLYWCH2
FLYWCH family member 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000293981
  • ENSP00000293981
  • ENSG00000162076
  • ENST00000396958
  • ENSP00000380159
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.88
protein complex
0.83
cell line
0.61
transcription factor
0.61
tissue sample
0.54


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.35   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 64   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.35   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 64   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (39)
RXRB
Tclin
Family:  NR
Novelty:  0.01503977
p_int:  0.999997123
p_ni:  0.000002805
p_wrong:  7.2e-8
Score:  0.527
Data Source:  BioPlex,STRINGDB
TBC1D23
Tbio
Novelty:  0.18566729
p_int:  0.999762863
p_ni:  0.000237127
p_wrong:  1e-8
Score:  0.638
Data Source:  BioPlex,STRINGDB
HSPA8
Tchem
Novelty:  0.00081014
p_int:  0.9972546
p_ni:  0.0027454
Data Source:  BioPlex
WDR54
Tdark
Novelty:  1.19807122
p_int:  0.996565476
p_ni:  0.003434524
Score:  0.167
Data Source:  BioPlex,STRINGDB
PCDHB11
Tdark
Novelty:  0.80480462
p_int:  0.995870466
p_ni:  0.004129468
p_wrong:  6.6e-8
Data Source:  BioPlex
PPARG
Tclin
Family:  NR
Novelty:  0.00010033
p_int:  0.980820823
p_ni:  0.019179176
Score:  0.282
Data Source:  BioPlex,STRINGDB
SELENBP1
Tbio
Novelty:  0.00758018
p_int:  0.976648563
p_ni:  0.023351436
p_wrong:  1e-9
Data Source:  BioPlex
HSPBP1
Tbio
Novelty:  0.01176285
p_int:  0.975304662
p_ni:  0.024695338
Score:  0.15
Data Source:  BioPlex,STRINGDB
CALML3
Tbio
Novelty:  0.0336689
p_int:  0.971175924
p_ni:  0.009727603
p_wrong:  0.019096473
Data Source:  BioPlex
SPATA1
Tdark
p_int:  0.955361063
p_ni:  0.044632977
p_wrong:  0.00000596
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations ()
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil percentage of leukocytes
2
2
2
87.5
eosinophil count
2
2
2
87.3
eosinophil percentage of granulocytes
1
1
1
59.6
neutrophil percentage of granulocytes
1
1
1
45.2
balding measurement
1
1
1
13.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil percentage of leukocytes
2
87.5
eosinophil count
2
87.3
eosinophil percentage of granulocytes
1
59.6
neutrophil percentage of granulocytes
1
45.2
balding measurement
1
13.1
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
FLYWCH family member 2
VGNC:5771
453847
Mouse
MGI:1924167
76917
Rat
RGD:11436072
108352059
Dog
FLYWCH family member 2
VGNC:40912
479872
Cow
FLYWCH family member 2
VGNC:50104
618572
Species
Name
OMA
EggNOG
Inparanoid
Chimp
FLYWCH family member 2
Mouse
Rat
Dog
FLYWCH family member 2
Cow
FLYWCH family member 2
Publication Statistics
PubMed Score 0.35
PubMed score by year
PubTator Score 0.20
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title