You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
FLYWCH1
FLYWCH-type zinc finger-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000253928
  • ENSP00000253928
  • ENSG00000059122
  • ENST00000416288
  • ENSP00000399938

Symbol
  • KIAA1552
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.74
tissue sample
0.69
disease perturbation
0.68
transcription factor binding site profile
0.56
kinase perturbation
0.54


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.8   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 52   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.8   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 52   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (23)
PLOD3
Tbio
Family:  Enzyme
Novelty:  0.02211629
p_int:  0.999840199
p_ni:  2.6e-8
p_wrong:  0.000159775
Data Source:  BioPlex
ANKRD9
Tdark
Novelty:  0.43181793
Score:  0.756
Data Source:  STRINGDB
MARCH3
Tbio
Family:  Enzyme
Novelty:  0.12529817
Score:  0.735
Data Source:  STRINGDB
MYO1G
Tbio
Novelty:  0.01119203
Score:  0.719
Data Source:  STRINGDB
AHRR
Tbio
Family:  TF
Novelty:  0.01361231
Score:  0.719
Data Source:  STRINGDB
MDC1
Tbio
Novelty:  0.00533097
Score:  0.693
Data Source:  STRINGDB
ACSM3
Tbio
Family:  Enzyme
Novelty:  0.02440917
Score:  0.677
Data Source:  STRINGDB
KIAA1586
Tdark
Novelty:  2.30999532
Score:  0.652
Data Source:  STRINGDB
OR1C1
Tdark
Family:  oGPCR
Novelty:  5.8313082
Score:  0.583
Data Source:  STRINGDB
FAM89B
Tbio
Novelty:  0.10306021
Score:  0.574
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (5)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
2
2
2
82
brain measurement
1
1
0
5.8
18.4
balding measurement
1
1
1
17.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
2
82
brain measurement
0
5.8
18.4
balding measurement
1
17.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
FLYWCH-type zinc finger 1
VGNC:13707
453851
Macaque
FLYWCH-type zinc finger 1
700909
Mouse
MGI:2442638
224613
Rat
RGD:1309385
360488
Dog
FLYWCH-type zinc finger 1
VGNC:40911
490052
Species
Name
OMA
EggNOG
Inparanoid
Chimp
FLYWCH-type zinc finger 1
Macaque
FLYWCH-type zinc finger 1
Mouse
Rat
Dog
FLYWCH-type zinc finger 1
Publication Statistics
PubMed Score 4.80
PubMed score by year
PubTator Score 1.17
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title